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A monoclonal antibody targeting a large surface of the receptor binding motif shows pan-neutralizing SARS-CoV-2 activity.
de Campos-Mata L, Trinité B, Modrego A, Tejedor Vaquero S, Pradenas E, Pons-Grífols A, Rodrigo Melero N, Carlero D, Marfil S, Santiago C, Raïch-Regué D, Bueno-Carrasco MT, Tarrés-Freixas F, Abancó F, Urrea V, Izquierdo-Useros N, Riveira-Muñoz E, Ballana E, Pérez M, Vergara-Alert J, Segalés J, Carolis C, Arranz R, Blanco J, Magri G. de Campos-Mata L, et al. Among authors: marfil s. Nat Commun. 2024 Feb 5;15(1):1051. doi: 10.1038/s41467-024-45171-9. Nat Commun. 2024. PMID: 38316751 Free PMC article.
Proteoliposomal formulations of an HIV-1 gp41-based miniprotein elicit a lipid-dependent immunodominant response overlapping the 2F5 binding motif.
Molinos-Albert LM, Bilbao E, Agulló L, Marfil S, García E, Rodríguez de la Concepción ML, Izquierdo-Useros N, Vilaplana C, Nieto-Garai JA, Contreras FX, Floor M, Cardona PJ, Martinez-Picado J, Clotet B, Villà-Freixa J, Lorizate M, Carrillo J, Blanco J. Molinos-Albert LM, et al. Among authors: marfil s. Sci Rep. 2017 Jan 13;7:40800. doi: 10.1038/srep40800. Sci Rep. 2017. PMID: 28084464 Free PMC article.
Impact of intensification with raltegravir on HIV-1-infected individuals receiving monotherapy with boosted PIs.
Puertas MC, Gómez-Mora E, Santos JR, Moltó J, Urrea V, Morón-López S, Hernández-Rodríguez A, Marfil S, Martínez-Bonet M, Matas L, Muñoz-Fernández MA, Clotet B, Blanco J, Martinez-Picado J. Puertas MC, et al. Among authors: marfil s. J Antimicrob Chemother. 2018 Jul 1;73(7):1940-1948. doi: 10.1093/jac/dky106. J Antimicrob Chemother. 2018. PMID: 29635527 Free PMC article. Clinical Trial.
HIV-1 envelope glycoproteins isolated from Viremic Non-Progressor individuals are fully functional and cytopathic.
Cabrera-Rodríguez R, Hebmann V, Marfil S, Pernas M, Marrero-Hernández S, Cabrera C, Urrea V, Casado C, Olivares I, Márquez-Arce D, Pérez-Yanes S, Estévez-Herrera J, Clotet B, Espert L, López-Galíndez C, Biard-Piechaczyk M, Valenzuela-Fernández A, Blanco J. Cabrera-Rodríguez R, et al. Among authors: marfil s. Sci Rep. 2019 Apr 3;9(1):5544. doi: 10.1038/s41598-019-42075-3. Sci Rep. 2019. PMID: 30944395 Free PMC article.
57 results