Bitter taste receptors as targets for tocolytics in preterm labor therapy.
Zheng K, Lu P, Delpapa E, Bellve K, Deng R, Condon JC, Fogarty K, Lifshitz LM, Simas TAM, Shi F, ZhuGe R.
Zheng K, et al. Among authors: lu p.
FASEB J. 2017 Sep;31(9):4037-4052. doi: 10.1096/fj.201601323RR. Epub 2017 May 30.
FASEB J. 2017.
PMID: 28559440
Free PMC article.
Collectively, our results reveal that activation of the canonical TAS2R signaling system in myometrial cells produces profound relaxation of myometrium precontracted by a broad spectrum of contractile agonists, and that targeting TAS2Rs is an attractive approach to developing eff …
Collectively, our results reveal that activation of the canonical TAS2R signaling system in myometrial cells produces profound relaxation of …