Fliegert R - Search Results

1

2'-deoxy-ADPR activates human TRPM2 faster than ADPR and thereby induces higher currents at physiological Ca²⁺ concentrations.

Pick J, Sander S, Etzold S, Rosche A, Tidow H, Guse AH, Fliegert R. Pick J, et al. Among authors: fliegert r. Front Immunol. 2024 Jan 22;15:1294357. doi: 10.3389/fimmu.2024.1294357. eCollection 2024. Front Immunol. 2024. PMID: 38318185 Free PMC article.

2

Potential role of the bitter taste receptor T2R14 in the prolonged survival and enhanced chemoresponsiveness induced by apigenin.

Stern L, Boehme LF, Goetz MR, Nitschke C, Giannou A, Zhang T, Güngör C, Reeh M, Izbicki JR, Fliegert R, Hausen A, Giese N, Hackert T, Niv MY, Heinrich S, Gaida MM, Ghadban T. Stern L, et al. Among authors: fliegert r. Int J Oncol. 2023 Jan;62(1):6. doi: 10.3892/ijo.2022.5454. Epub 2022 Nov 16. Int J Oncol. 2023. PMID: 36382671 Free PMC article.

3

Human dental pulp cells modulate CD8⁺ T cell proliferation and efficiently degrade extracellular ATP to adenosine in vitro.

Ahmadi P, Yan M, Bauche A, Smeets R, Müller CE, Koch-Nolte F, Haag F, Fliegert R, Kluwe L, Schulze Zur Wiesch J, Hartjen P. Ahmadi P, et al. Among authors: fliegert r. Cell Immunol. 2022 Oct;380:104589. doi: 10.1016/j.cellimm.2022.104589. Epub 2022 Aug 13. Cell Immunol. 2022. PMID: 36084401

4

The crystal structure of TRPM2 MHR1/2 domain reveals a conserved Zn²⁺ -binding domain essential for structural integrity and channel activity.

Sander S, Pick J, Gattkowski E, Fliegert R, Tidow H. Sander S, et al. Among authors: fliegert r. Protein Sci. 2022 Jun;31(6):e4320. doi: 10.1002/pro.4320. Protein Sci. 2022. PMID: 35634784 Free PMC article.

5

cADPR Does Not Activate TRPM2.

Riekehr WM, Sander S, Pick J, Tidow H, Bauche A, Guse AH, Fliegert R. Riekehr WM, et al. Among authors: fliegert r. Int J Mol Sci. 2022 Mar 15;23(6):3163. doi: 10.3390/ijms23063163. Int J Mol Sci. 2022. PMID: 35328585 Free PMC article.

6

CD73-mediated adenosine production by CD8 T cell-derived extracellular vesicles constitutes an intrinsic mechanism of immune suppression.

Schneider E, Winzer R, Rissiek A, Ricklefs I, Meyer-Schwesinger C, Ricklefs FL, Bauche A, Behrends J, Reimer R, Brenna S, Wasielewski H, Lauten M, Rissiek B, Puig B, Cortesi F, Magnus T, Fliegert R, Müller CE, Gagliani N, Tolosa E. Schneider E, et al. Among authors: fliegert r. Nat Commun. 2021 Oct 8;12(1):5911. doi: 10.1038/s41467-021-26134-w. Nat Commun. 2021. PMID: 34625545 Free PMC article.

7

Mouse CD38-Specific Heavy Chain Antibodies Inhibit CD38 GDPR-Cyclase Activity and Mediate Cytotoxicity Against Tumor Cells.

Baum N, Eggers M, Koenigsdorf J, Menzel S, Hambach J, Staehler T, Fliegert R, Kulow F, Adam G, Haag F, Bannas P, Koch-Nolte F. Baum N, et al. Among authors: fliegert r. Front Immunol. 2021 Sep 3;12:703574. doi: 10.3389/fimmu.2021.703574. eCollection 2021. Front Immunol. 2021. PMID: 34539634 Free PMC article.

8

Analysis of ligand binding and resulting conformational changes in pyrophosphatase NUDT9.

Gattkowski E, Rutherford TJ, Möckl F, Bauche A, Sander S, Fliegert R, Tidow H. Gattkowski E, et al. Among authors: fliegert r. FEBS J. 2021 Dec;288(23):6769-6782. doi: 10.1111/febs.16097. Epub 2021 Jul 13. FEBS J. 2021. PMID: 34189846 Free PMC article.

9

HN1L/JPT2: A signaling protein that connects NAADP generation to Ca²⁺ microdomain formation.

Roggenkamp HG, Khansahib I, Hernandez C LC, Zhang Y, Lodygin D, Krüger A, Gu F, Möckl F, Löhndorf A, Wolters V, Woike D, Rosche A, Bauche A, Schetelig D, Werner R, Schlüter H, Failla AV, Meier C, Fliegert R, Walseth TF, Flügel A, Diercks BP, Guse AH. Roggenkamp HG, et al. Among authors: fliegert r. Sci Signal. 2021 Mar 23;14(675):eabd5647. doi: 10.1126/scisignal.abd5647. Sci Signal. 2021. PMID: 33758062

10

Daratumumab and Nanobody-Based Heavy Chain Antibodies Inhibit the ADPR Cyclase but not the NAD⁺ Hydrolase Activity of CD38-Expressing Multiple Myeloma Cells.

Baum N, Fliegert R, Bauche A, Hambach J, Menzel S, Haag F, Bannas P, Koch-Nolte F. Baum N, et al. Among authors: fliegert r. Cancers (Basel). 2020 Dec 30;13(1):76. doi: 10.3390/cancers13010076. Cancers (Basel). 2020. PMID: 33396591 Free PMC article.

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