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FicD Sensitizes Cellular Response to Glucose Fluctuations in Mouse Embryonic Fibroblasts.
Gulen B, Kinch LN, Servage KA, Blevins A, Stewart NM, Gray HF, Casey AK, Orth K. Gulen B, et al. Among authors: gray hf. bioRxiv [Preprint]. 2024 Jan 23:2024.01.22.576705. doi: 10.1101/2024.01.22.576705. bioRxiv. 2024. Update in: Proc Natl Acad Sci U S A. 2024 Sep 17;121(38):e2400781121. doi: 10.1073/pnas.2400781121 PMID: 38328056 Free PMC article. Updated. Preprint.
Identification and Optimization of a Ligand-Efficient Benzoazepinone Bromodomain and Extra Terminal (BET) Family Acetyl-Lysine Mimetic into the Oral Candidate Quality Molecule I-BET432.
Humphreys PG, Anderson NA, Bamborough P, Baxter A, Chung CW, Cookson R, Craggs PD, Dalton T, Fournier JCL, Gordon LJ, Gray HF, Gray MW, Gregory R, Hirst DJ, Jamieson C, Jones KL, Kessedjian H, Lugo D, McGonagle G, Patel VK, Patten C, Poole DL, Prinjha RK, Ramirez-Molina C, Rioja I, Seal G, Stafford KAJ, Shah RR, Tape D, Theodoulou NH, Tomlinson L, Ukuser S, Wall ID, Wellaway N, White G. Humphreys PG, et al. Among authors: gray hf. J Med Chem. 2022 Nov 24;65(22):15174-15207. doi: 10.1021/acs.jmedchem.2c01102. Epub 2022 Nov 15. J Med Chem. 2022. PMID: 36378954
Fic-mediated AMPylation tempers the unfolded protein response during physiological stress.
Casey AK, Gray HF, Chimalapati S, Hernandez G, Moehlman AT, Stewart N, Fields HA, Gulen B, Servage KA, Stefanius K, Blevins A, Evers BM, Krämer H, Orth K. Casey AK, et al. Among authors: gray hf. Proc Natl Acad Sci U S A. 2022 Aug 9;119(32):e2208317119. doi: 10.1073/pnas.2208317119. Epub 2022 Aug 1. Proc Natl Acad Sci U S A. 2022. PMID: 35914137 Free PMC article.
A calcium channel mutant mouse model of hypokalemic periodic paralysis.
Wu F, Mi W, Hernández-Ochoa EO, Burns DK, Fu Y, Gray HF, Struyk AF, Schneider MF, Cannon SC. Wu F, et al. Among authors: gray hf. J Clin Invest. 2012 Dec;122(12):4580-91. doi: 10.1172/JCI66091. Epub 2012 Nov 26. J Clin Invest. 2012. PMID: 23187123 Free PMC article.
25 results