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Systematic evaluation of B-cell clonal family inference approaches.
Balashova D, van Schaik BDC, Stratigopoulou M, Guikema JEJ, Caniels TG, Claireaux M, van Gils MJ, Musters A, Anang DC, de Vries N, Greiff V, van Kampen AHC. Balashova D, et al. Among authors: guikema jej. BMC Immunol. 2024 Feb 8;25(1):13. doi: 10.1186/s12865-024-00600-8. BMC Immunol. 2024. PMID: 38331731 Free PMC article.
Core regions in immunoglobulin heavy chain enhancers essential for survival of non-Hodgkin lymphoma cells are identified by a CRISPR interference screen.
Kasprzyk ME, Sura W, Podralska M, Kazimierska M, Seitz A, Łosiewski W, Woźniak T, Guikema JEJ, Diepstra A, Kluiver J, Van den Berg A, Rozwadowska N, Dzikiewicz-Krawczyk A. Kasprzyk ME, et al. Among authors: guikema jej. Haematologica. 2024 Jun 27. doi: 10.3324/haematol.2023.284672. Online ahead of print. Haematologica. 2024. PMID: 38934080 Free article.
Understanding repertoire sequencing data through a multiscale computational model of the germinal center.
García-Valiente R, Merino Tejero E, Stratigopoulou M, Balashova D, Jongejan A, Lashgari D, Pélissier A, Caniels TG, Claireaux MAF, Musters A, van Gils MJ, Rodríguez Martínez M, de Vries N, Meyer-Hermann M, Guikema JEJ, Hoefsloot H, van Kampen AHC. García-Valiente R, et al. Among authors: guikema jej. NPJ Syst Biol Appl. 2023 Mar 16;9(1):8. doi: 10.1038/s41540-023-00271-y. NPJ Syst Biol Appl. 2023. PMID: 36927990 Free PMC article.
Huwe1 supports B-cell development, B-cell-dependent immunity, somatic hypermutation and class switch recombination by regulating proliferation.
Spanjaard A, Stratigopoulou M, de Groot D, Aslam M, van den Berk PCM, Stappenbelt C, Ayidah M, Catsman JJI, Pardieck IN, Kreft M, Arens R, Guikema JEJ, Jacobs H. Spanjaard A, et al. Among authors: guikema jej. Front Immunol. 2023 Jan 9;13:986863. doi: 10.3389/fimmu.2022.986863. eCollection 2022. Front Immunol. 2023. PMID: 36700204 Free PMC article.
SMG1, a nonsense-mediated mRNA decay (NMD) regulator, as a candidate therapeutic target in multiple myeloma.
Leeksma AC, Derks IAM, Garrick B, Jongejan A, Colombo M, Bloedjes T, Trowe T, Leisten JC, Howarth M, Malek M, Mortensen DS, Blease K, Groza MC, Narla RK, Loos R, Kersten MJ, Moerland PD, Guikema JEJ, Kater AP, Eldering E, Filvaroff EH. Leeksma AC, et al. Among authors: guikema jej. Mol Oncol. 2023 Feb;17(2):284-297. doi: 10.1002/1878-0261.13343. Epub 2022 Dec 16. Mol Oncol. 2023. PMID: 36400430 Free PMC article.
57 results