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Structural studies and cytotoxicity assays of "aggregation-prone" IAPP(8-16) and its non-amyloidogenic variants suggest its important role in fibrillogenesis and cytotoxicity of human amylin.
Louros NN, Tsiolaki PL, Zompra AA, Pappa EV, Magafa V, Pairas G, Cordopatis P, Cheimonidou C, Trougakos IP, Iconomidou VA, Hamodrakas SJ. Louros NN, et al. Among authors: cordopatis p. Biopolymers. 2015 May;104(3):196-205. doi: 10.1002/bip.22650. Biopolymers. 2015. PMID: 25913357
Involvement of angiotensin II type 2 receptor (AT2R) signaling in human pancreatic ductal adenocarcinoma (PDAC): a novel AT2R agonist effectively attenuates growth of PDAC grafts in mice.
Ishiguro S, Yoshimura K, Tsunedomi R, Oka M, Takao S, Inui M, Kawabata A, Wall T, Magafa V, Cordopatis P, Tzakos AG, Tamura M. Ishiguro S, et al. Among authors: cordopatis p. Cancer Biol Ther. 2015;16(2):307-16. doi: 10.1080/15384047.2014.1002357. Cancer Biol Ther. 2015. PMID: 25756513 Free PMC article.
Electronic sculpting of ligand-GPCR subtype selectivity: the case of angiotensin II.
Magnani F, Pappas CG, Crook T, Magafa V, Cordopatis P, Ishiguro S, Ohta N, Selent J, Bosnyak S, Jones ES, Gerothanassis IP, Tamura M, Widdop RE, Tzakos AG. Magnani F, et al. Among authors: cordopatis p. ACS Chem Biol. 2014 Jul 18;9(7):1420-5. doi: 10.1021/cb500063y. Epub 2014 May 14. ACS Chem Biol. 2014. PMID: 24787922 Free PMC article.
93 results