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Page 1
p63 controls metabolic activation of hepatic stellate cells and fibrosis via an HER2-ACC1 pathway.
Fondevila MF, Novoa E, Gonzalez-Rellan MJ, Fernandez U, Heras V, Porteiro B, Parracho T, Dorta V, Riobello C, da Silva Lima N, Seoane S, Garcia-Vence M, Chantada-Vazquez MP, Bravo SB, Senra A, Leiva M, Marcos M, Sabio G, Perez-Fernandez R, Dieguez C, Prevot V, Schwaninger M, Woodhoo A, Martinez-Chantar ML, Schwabe R, Cubero FJ, Varela-Rey M, Crespo J, Iruzubieta P, Nogueiras R. Fondevila MF, et al. Among authors: sabio g. Cell Rep Med. 2024 Feb 20;5(2):101401. doi: 10.1016/j.xcrm.2024.101401. Epub 2024 Feb 9. Cell Rep Med. 2024. PMID: 38340725 Free PMC article.
Plasma membrane remodeling determines adipocyte expansion and mechanical adaptability.
Aboy-Pardal MCM, Guadamillas MC, Guerrero CR, Català-Montoro M, Toledano-Donado M, Terrés-Domínguez S, Pavón DM, Jiménez-Jiménez V, Jimenez-Carretero D, Zamai M, Folgueira C, Cerezo A, Lolo FN, Nogueiras R, Sabio G, Sánchez-Álvarez M, Echarri A, Garcia R, Del Pozo MA. Aboy-Pardal MCM, et al. Among authors: sabio g. Nat Commun. 2024 Nov 28;15(1):10102. doi: 10.1038/s41467-024-54224-y. Nat Commun. 2024. PMID: 39609408 Free PMC article.
The dual GLP-1/glucagon receptor agonist G49 mimics bariatric surgery effects by inducing metabolic rewiring and inter-organ crosstalk.
Valdecantos MP, Ruiz L, Folgueira C, Rada P, Gomez-Santos B, Solas M, Hitos AB, Field J, Francisco V, Escalona-Garrido C, Zagmutt S, Calderon-Dominguez M, Mera P, Garcia-Martinez I, Maymó-Masip E, Grajales D, Alen R, Mora A, Sáinz N, Vides-Urrestarazu I, Vilarrasa N, Arbones-Mainar JM, Zaragoza C, Moreno-Aliaga MJ, Aspichueta P, Fernández-Veledo S, Vendrell J, Serra D, Herrero L, Schreiber R, Zechner R, Sabio G, Hornigold D, Rondinone CM, Jermutus L, Grimsby J, Valverde ÁM. Valdecantos MP, et al. Among authors: sabio g. Nat Commun. 2024 Nov 28;15(1):10342. doi: 10.1038/s41467-024-54080-w. Nat Commun. 2024. PMID: 39609390 Free PMC article.
Protein kinase D2 modulates hepatic insulin sensitivity in male mice.
Rada P, Carceller-López E, Hitos AB, Gómez-Santos B, Fernández-Hernández C, Rey E, Pose-Utrilla J, García-Monzón C, González-Rodríguez Á, Sabio G, García A, Aspichueta P, Iglesias T, Valverde ÁM. Rada P, et al. Among authors: sabio g. Mol Metab. 2024 Dec;90:102045. doi: 10.1016/j.molmet.2024.102045. Epub 2024 Oct 12. Mol Metab. 2024. PMID: 39401614 Free PMC article.
p38α kinase governs muscle strength through PGC1α in mice.
Herrera-Melle L, Cicuéndez B, López JA, Dumesic PA, Wilensky SE, Rodríguez E, Leiva-Vega L, Caballero A, León M, Vázquez J, Spiegelman BM, Folgueira C, Mora A, Sabio G. Herrera-Melle L, et al. Among authors: sabio g. Acta Physiol (Oxf). 2024 Nov;240(11):e14234. doi: 10.1111/apha.14234. Epub 2024 Oct 3. Acta Physiol (Oxf). 2024. PMID: 39361268
p38γ/δ activation alters cardiac electrical activity and predisposes to ventricular arrhythmia.
Romero-Becerra R, Cruz FM, Mora A, Lopez JA, Ponce-Balbuena D, Allan A, Ramos-Mondragón R, González-Terán B, León M, Rodríguez ME, Leiva-Vega L, Guerrero-Serna G, Jimenez-Vazquez EN, Filgueiras-Rama D, Vázquez J, Jalife J, Sabio G. Romero-Becerra R, et al. Among authors: sabio g. Nat Cardiovasc Res. 2023 Dec;2(12):1204-1220. doi: 10.1038/s44161-023-00368-x. Epub 2023 Nov 27. Nat Cardiovasc Res. 2023. PMID: 39196141
Remodeling p38 signaling in muscle controls locomotor activity via IL-15.
Folgueira C, Herrera-Melle L, López JA, Galvan-Alvarez V, Martin-Rincon M, Cuartero MI, García-Culebras A, Dumesic PA, Rodríguez E, Leiva-Vega L, León M, Porteiro B, Iglesias C, Torres JL, Hernández-Cosido L, Bonacasa C, Marcos M, Moro MÁ, Vázquez J, Calbet JAL, Spiegelman BM, Mora A, Sabio G. Folgueira C, et al. Among authors: sabio g. Sci Adv. 2024 Aug 16;10(33):eadn5993. doi: 10.1126/sciadv.adn5993. Epub 2024 Aug 14. Sci Adv. 2024. PMID: 39141732 Free PMC article.
Estrogens prevent the hypothalamus-periphery crosstalk induced by olanzapine intraperitoneal treatment in female mice: Effects on brown/beige adipose tissues and liver.
Ferreira V, Folgueira C, Montes-San Lorenzo Á, Rodríguez-López A, Gonzalez-Iglesias E, Zubiaur P, Abad-Santos F, Sabio G, Rada P, Valverde ÁM. Ferreira V, et al. Among authors: sabio g. Biochim Biophys Acta Mol Basis Dis. 2024 Jun;1870(5):167227. doi: 10.1016/j.bbadis.2024.167227. Epub 2024 May 11. Biochim Biophys Acta Mol Basis Dis. 2024. PMID: 38733774 Free article.
Lack of p38 activation in T cells increases IL-35 and protects against obesity by promoting thermogenesis.
Nikolic I, Ruiz-Garrido I, Crespo M, Romero-Becerra R, Leiva-Vega L, Mora A, León M, Rodríguez E, Leiva M, Plata-Gómez AB, Alvarez Flores MB, Torres JL, Hernández-Cosido L, López JA, Vázquez J, Efeyan A, Martin P, Marcos M, Sabio G. Nikolic I, et al. Among authors: sabio g. EMBO Rep. 2024 Jun;25(6):2635-2661. doi: 10.1038/s44319-024-00149-y. Epub 2024 May 10. EMBO Rep. 2024. PMID: 38730210 Free PMC article.
95 results