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Colostrum is required for the postnatal ontogeny of small intestine innate lymphoid type 2 cells and successful anti-helminth defences.
Rekima A, van den Elsen L, Isnard C, Smyth DJ, Lynn MA, Yee T, Stevens NE, Machado S, Divakara N, Bhasin M, Tjiam MC, Rowel C, Servant F, Burcelin R, Locksley R, Maizels R, Lynn DJ, Egwang T, Verhasselt V. Rekima A, et al. Among authors: maizels r. Allergy. 2024 Aug;79(8):2247-2251. doi: 10.1111/all.16054. Epub 2024 Feb 13. Allergy. 2024. PMID: 38348877 No abstract available.
The helminth TGF-β mimic TGM4 is a modular ligand that binds CD44, CD49d and TGF-β receptors to preferentially target myeloid cells.
Singh SP, Smyth DJ, Cunningham K, Mukundan A, Byeon CH, Hinck CS, White MPJ, Ciancia C, Wosowska N, Sanders A, Jin R, Lilla S, Zanivan S, Schoenherr C, Inman G, van Dinther M, Ten Dijke P, Hinck AP, Maizels RM. Singh SP, et al. Among authors: maizels rm. bioRxiv [Preprint]. 2023 Nov 15:2023.11.13.566701. doi: 10.1101/2023.11.13.566701. bioRxiv. 2023. PMID: 38014296 Free PMC article. Preprint.
Tuft cell acetylcholine is released into the gut lumen to promote anti-helminth immunity.
Ndjim M, Gasmi I, Herbert F, Joséphine C, Bas J, Lamrani A, Coutry N, Henry S, Zimmermann VS, Dardalhon V, Campillo Poveda M, Turtoi E, Thirard S, Forichon L, Giordano A, Ciancia C, Homayed Z, Pannequin J, Britton C, Devaney E, McNeilly TN, Berrard S, Turtoi A, Maizels RM, Gerbe F, Jay P. Ndjim M, et al. Among authors: maizels rm. Immunity. 2024 Jun 11;57(6):1260-1273.e7. doi: 10.1016/j.immuni.2024.04.018. Epub 2024 May 13. Immunity. 2024. PMID: 38744292 Free article.
New technologies to study helminth development and host-parasite interactions.
Britton C, Laing R, McNeilly TN, Perez MG, Otto TD, Hildersley KA, Maizels RM, Devaney E, Gillan V. Britton C, et al. Among authors: maizels rm. Int J Parasitol. 2023 Jul;53(8):393-403. doi: 10.1016/j.ijpara.2022.11.012. Epub 2023 Mar 16. Int J Parasitol. 2023. PMID: 36931423 Free article. Review.
370 results