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Page 1
Internal regulation between constitutively expressed T cell co-inhibitory receptors BTLA and CD5 and tolerance in recent thymic emigrants.
Adegoke AO, Thangavelu G, Chou TF, Petersen MI, Kakugawa K, May JF, Joannou K, Wang Q, Ellestad KK, Boon L, Bretscher PA, Cheroutre H, Kronenberg M, Baldwin TA, Anderson CC. Adegoke AO, et al. Among authors: thangavelu g. Open Biol. 2024 Oct;14(10):240178. doi: 10.1098/rsob.240178. Epub 2024 Oct 30. Open Biol. 2024. PMID: 39471840 Free PMC article.
Corticosteroids impair epithelial regeneration in immune-mediated intestinal damage.
Arnhold V, Chang WY, Jansen SA, Thangavelu G, Calafiore M, Vinci P, Fu YY, Ito T, Takashima S, Egorova A, Kuttiyara J, Perlstein A, van Hoesel M, Liu C, Blazar BR, Lindemans CA, Hanash AM. Arnhold V, et al. Among authors: thangavelu g. J Clin Invest. 2024 Feb 13;134(7):e155880. doi: 10.1172/JCI155880. J Clin Invest. 2024. PMID: 38349762 Free PMC article.
Enforced gut homing of murine regulatory T cells reduces early graft-versus-host disease severity.
Larson JH, Jin S, Loschi M, Bolivar Wagers S, Thangavelu G, Zaiken MC, McDonald-Hyman C, Saha A, Aguilar EG, Koehn B, Osborn MJ, Panoskaltsis-Mortari A, Macdonald KPA, Hill GR, Murphy WJ, Serody JS, Maillard I, Kean LS, Kim SV, Littman DR, Blazar BR. Larson JH, et al. Among authors: thangavelu g. Am J Transplant. 2023 Aug;23(8):1102-1115. doi: 10.1016/j.ajt.2023.01.030. Epub 2023 Mar 4. Am J Transplant. 2023. PMID: 36878433 Free PMC article.
Prevention of acute GVHD using an orthogonal IL-2/IL-2Rβ system to selectively expand regulatory T cells in vivo.
Ramos TL, Bolivar-Wagers S, Jin S, Thangavelu G, Simonetta F, Lin PY, Hirai T, Saha A, Koehn B, Su LL, Picton LK, Baker J, Lohmeyer JK, Riddle M, Eide C, Tolar J, Panoskaltsis-Mortari A, Wagner JE, Garcia KC, Negrin RS, Blazar BR. Ramos TL, et al. Among authors: thangavelu g. Blood. 2023 Mar 16;141(11):1337-1352. doi: 10.1182/blood.2022018440. Blood. 2023. PMID: 36564052 Free PMC article.
Retinoic acid signaling acts as a rheostat to balance Treg function.
Thangavelu G, Andrejeva G, Bolivar-Wagers S, Jin S, Zaiken MC, Loschi M, Aguilar EG, Furlan SN, Brown CC, Lee YC, Hyman CM, Feser CJ, Panoskaltsis-Mortari A, Hippen KL, MacDonald KP, Murphy WJ, Maillard I, Hill GR, Munn DH, Zeiser R, Kean LS, Rathmell JC, Chi H, Noelle RJ, Blazar BR. Thangavelu G, et al. Cell Mol Immunol. 2022 Jul;19(7):820-833. doi: 10.1038/s41423-022-00869-y. Epub 2022 May 17. Cell Mol Immunol. 2022. PMID: 35581350 Free PMC article.
BET-bromodomain and EZH2 inhibitor-treated chronic GVHD mice have blunted germinal centers with distinct transcriptomes.
Zaiken MC, Flynn R, Paz KG, Rhee SY, Jin S, Mohamed FA, Saha A, Thangavelu G, Park PMC, Hemming ML, Sage PT, Sharpe AH, DuPage M, Bluestone JA, Panoskaltsis-Mortari A, Cutler CS, Koreth J, Antin JH, Soiffer RJ, Ritz J, Luznik L, Maillard I, Hill GR, MacDonald KPA, Munn DH, Serody JS, Murphy WJ, Kean LS, Zhang Y, Bradner JE, Qi J, Blazar BR. Zaiken MC, et al. Among authors: thangavelu g. Blood. 2022 May 12;139(19):2983-2997. doi: 10.1182/blood.2021014557. Blood. 2022. PMID: 35226736 Free PMC article.
36 results