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Third-generation taxanes SB-T-121605 and SB-T-121606 are effective in pancreatic ductal adenocarcinoma.
Sychra T, Spalenkova A, Balatka S, Vaclavikova R, Seborova K, Ehrlichova M, Truksa J, Sandoval-Acuña C, Nemcova V, Szabo A, Koci K, Tesarova T, Chen L, Ojima I, Oliverius M, Soucek P. Sychra T, et al. Among authors: sandoval acuna c. iScience. 2024 Jan 26;27(2):109044. doi: 10.1016/j.isci.2024.109044. eCollection 2024 Feb 16. iScience. 2024. PMID: 38357661 Free PMC article.
Anticancer regimens containing third generation taxanes SB-T-121605 and SB-T-121606 are highly effective in resistant ovarian carcinoma model.
Seborova K, Koucka K, Spalenkova A, Holy P, Ehrlichova M, Sychra T, Chen L, Bendale H, Ojima I, Sandoval-Acuña C, Truksa J, Soucek P, Vaclavikova R. Seborova K, et al. Among authors: sandoval acuna c. Front Pharmacol. 2022 Nov 9;13:971905. doi: 10.3389/fphar.2022.971905. eCollection 2022. Front Pharmacol. 2022. PMID: 36438837 Free PMC article.
Complex Mitochondrial Dysfunction Induced by TPP+-Gentisic Acid and Mitochondrial Translation Inhibition by Doxycycline Evokes Synergistic Lethality in Breast Cancer Cells.
Fuentes-Retamal S, Sandoval-Acuña C, Peredo-Silva L, Guzmán-Rivera D, Pavani M, Torrealba N, Truksa J, Castro-Castillo V, Catalán M, Kemmerling U, Urra FA, Ferreira J. Fuentes-Retamal S, et al. Among authors: sandoval acuna c. Cells. 2020 Feb 11;9(2):407. doi: 10.3390/cells9020407. Cells. 2020. PMID: 32053908 Free PMC article.
Reactivation of Dihydroorotate Dehydrogenase-Driven Pyrimidine Biosynthesis Restores Tumor Growth of Respiration-Deficient Cancer Cells.
Bajzikova M, Kovarova J, Coelho AR, Boukalova S, Oh S, Rohlenova K, Svec D, Hubackova S, Endaya B, Judasova K, Bezawork-Geleta A, Kluckova K, Chatre L, Zobalova R, Novakova A, Vanova K, Ezrova Z, Maghzal GJ, Magalhaes Novais S, Olsinova M, Krobova L, An YJ, Davidova E, Nahacka Z, Sobol M, Cunha-Oliveira T, Sandoval-Acuña C, Strnad H, Zhang T, Huynh T, Serafim TL, Hozak P, Sardao VA, Koopman WJH, Ricchetti M, Oliveira PJ, Kolar F, Kubista M, Truksa J, Dvorakova-Hortova K, Pacak K, Gurlich R, Stocker R, Zhou Y, Berridge MV, Park S, Dong L, Rohlena J, Neuzil J. Bajzikova M, et al. Among authors: sandoval acuna c. Cell Metab. 2019 Feb 5;29(2):399-416.e10. doi: 10.1016/j.cmet.2018.10.014. Epub 2018 Nov 15. Cell Metab. 2019. PMID: 30449682 Free PMC article.
Derivatives of alkyl gallate triphenylphosphonium exhibit antitumor activity in a syngeneic murine model of mammary adenocarcinoma.
Peredo-Silva L, Fuentes-Retamal S, Sandoval-Acuña C, Pavani M, Maya JD, Castro-Castillo V, Madrid-Rojas M, Rebolledo S, Kemmerling U, Parra E, Ferreira J. Peredo-Silva L, et al. Among authors: sandoval acuna c. Toxicol Appl Pharmacol. 2017 Aug 15;329:334-346. doi: 10.1016/j.taap.2017.06.017. Epub 2017 Jun 21. Toxicol Appl Pharmacol. 2017. PMID: 28647477
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