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Tissue-colonizing disseminated tumor cells secrete prostaglandin E2 to promote NK cell dysfunction and evade anti-metastatic immunity.
Pedde AM, Kim H, Donakonda S, Baumann T, Bayerl F, Meiser P, Hirschberger A, Klement C, Grassmann S, Öllinger R, Hüser N, Hartmann D, Laschinger M, Trapani JA, Zippelius A, Bald T, Wiedemann GM, Rad R, Sun JC, Höchst B, Böttcher JP. Pedde AM, et al. Among authors: bald t. Cell Rep. 2024 Nov 26;43(11):114855. doi: 10.1016/j.celrep.2024.114855. Epub 2024 Nov 13. Cell Rep. 2024. PMID: 39541209 Free article.
Type I Interferon Drives a Cellular State Inert to TCR-Stimulation and Could Impede Effective T-Cell Differentiation in Cancer.
Corvino D, Batstone M, Hughes BGM, Kempchen T, Ng SS, Salim N, Schneppenheim F, Rommel D, Kumar A, Pearson S, Madore J, Koufariotis LT, Steinheuer LM, Pathirana D, Thurley K, Hölzel M, Borcherding N, Braun M, Bald T. Corvino D, et al. Among authors: bald t. Eur J Immunol. 2024 Nov 12:e202451371. doi: 10.1002/eji.202451371. Online ahead of print. Eur J Immunol. 2024. PMID: 39529512
Preclinical evidence for the use of anti-Trop-2 antibody-drug conjugate Sacituzumab govitecan in cerebral metastasized castration-resistant prostate cancer.
Weiten R, Niemann M, Below E, Friker LL, Ralser DJ, Toma M, Kristiansen G, Hahn O, Zechel S, Grünwald V, Bald T, Siewert J, Pietsch T, Ritter M, Hölzel M, Eckstein M, Alajati A, Krausewitz P, Klümper N. Weiten R, et al. Among authors: bald t. Cancer Med. 2024 Jun;13(12):e7320. doi: 10.1002/cam4.7320. Cancer Med. 2024. PMID: 38895886 Free PMC article.
Author Correction: Tumor immunoevasion by the conversion of effector NK cells into type 1 innate lymphoid cell.
Gao Y, Souza-Fonseca-Guimaraes F, Bald T, Ng SS, Young A, Ngiow SF, Rautela J, Straube J, Waddell N, Blake SJ, Yan J, Bartholin L, Lee JS, Vivier E, Takeda K, Messaoudene M, Zitvogel L, Teng MWL, Belz GT, Engwerda CR, Huntington ND, Nakamura K, Hölzel M, Smyth MJ. Gao Y, et al. Among authors: bald t. Nat Immunol. 2024 May;25(5):925-926. doi: 10.1038/s41590-024-01799-9. Nat Immunol. 2024. PMID: 38514890 No abstract available.
Author Correction: The NK cell granule protein NKG7 regulates cytotoxic granule exocytosis and inflammation.
Ng SS, De Labastida Rivera F, Yan J, Corvino D, Das I, Zhang P, Kuns R, Chauhan SB, Hou J, Li XY, Frame TCM, McEnroe BA, Moore E, Na J, Engel JA, Soon MSF, Singh B, Kueh AJ, Herold MJ, Montes de Oca M, Singh SS, Bunn PT, Aguilera AR, Casey M, Braun M, Ghazanfari N, Wani S, Wang Y, Amante FH, Edwards CL, Haque A, Dougall WC, Singh OP, Baxter AG, Teng MWL, Loukas A, Daly NL, Cloonan N, Degli-Esposti MA, Uzonna J, Heath WR, Bald T, Tey SK, Nakamura K, Hill GR, Kumar R, Sundar S, Smyth MJ, Engwerda CR. Ng SS, et al. Among authors: bald t. Nat Immunol. 2024 Apr;25(4):716. doi: 10.1038/s41590-024-01770-8. Nat Immunol. 2024. PMID: 38360937 No abstract available.
Adipocyte Precursor-Derived NRG1 Promotes Resistance to FGFR Inhibition in Urothelial Carcinoma.
Hosni S, Kilian V, Klümper N, Gabbia D, Sieckmann K, Corvino D, Winkler A, Saponaro M, Wörsdörfer K, Schmidt D, Hahn O, Zanotto I, Bertlich M, Toma M, Bald T, Eckstein M, Hölzel M, Geyer M, Ritter M, Wachten D, De Martin S, Alajati A. Hosni S, et al. Among authors: bald t. Cancer Res. 2024 Mar 4;84(5):725-740. doi: 10.1158/0008-5472.CAN-23-1398. Cancer Res. 2024. PMID: 38175774 Free PMC article.
A replicating LCMV-based vaccine for the treatment of solid tumors.
Purde MT, Cupovic J, Palmowski YA, Makky A, Schmidt S, Rochwarger A, Hartmann F, Stemeseder F, Lercher A, Abdou MT, Bomze D, Besse L, Berner F, Tüting T, Hölzel M, Bergthaler A, Kochanek S, Ludewig B, Lauterbach H, Orlinger KK, Bald T, Schietinger A, Schürch C, Ring SS, Flatz L. Purde MT, et al. Among authors: bald t. Mol Ther. 2024 Feb 7;32(2):426-439. doi: 10.1016/j.ymthe.2023.11.026. Epub 2023 Dec 5. Mol Ther. 2024. PMID: 38058126 Free article.
74 results