Wen W - Search Results

1

Decoding the complexity of on-target integration: characterizing DNA insertions at the CRISPR-Cas9 targeted locus using nanopore sequencing.

Zhao JJ, Sun XY, Tian SN, Zhao ZZ, Yin MD, Zhao M, Zhang F, Li SA, Yang ZX, Wen W, Cheng T, Gong A, Zhang JP, Zhang XB. Zhao JJ, et al. Among authors: wen w. BMC Genomics. 2024 Feb 17;25(1):189. doi: 10.1186/s12864-024-10050-6. BMC Genomics. 2024. PMID: 38368357 Free PMC article.

2

[Establishment of Integration-Free Human Induced Pluripotent Stem Cells from A Patient with Primary Myelofibrosis].

Xu J, Sheng MY, Zhou Y, Xing W, Bai J, Wen W, Ji GZ, Zhang HY, Jin H, Lyu CC, Yuan WP, Zhang XB, Cheng T. Xu J, et al. Among authors: wen w. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2015 Oct;23(5):1415-21. doi: 10.7534/j.issn.1009-2137.2015.05.037. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2015. PMID: 26524049 Chinese.

3

Enhanced Generation of Integration-free iPSCs from Human Adult Peripheral Blood Mononuclear Cells with an Optimal Combination of Episomal Vectors.

Wen W, Zhang JP, Xu J, Su RJ, Neises A, Ji GZ, Yuan W, Cheng T, Zhang XB. Wen W, et al. Stem Cell Reports. 2016 Jun 14;6(6):873-884. doi: 10.1016/j.stemcr.2016.04.005. Epub 2016 May 5. Stem Cell Reports. 2016. PMID: 27161365 Free PMC article.

4

Generation of Integration-free Induced Pluripotent Stem Cells from Human Peripheral Blood Mononuclear Cells Using Episomal Vectors.

Wen W, Zhang JP, Chen W, Arakaki C, Li X, Baylink D, Botimer GD, Xu J, Yuan W, Cheng T, Zhang XB. Wen W, et al. J Vis Exp. 2017 Jan 1;(119):55091. doi: 10.3791/55091. J Vis Exp. 2017. PMID: 28117800 Free PMC article.

5

Efficient precise knockin with a double cut HDR donor after CRISPR/Cas9-mediated double-stranded DNA cleavage.

Zhang JP, Li XL, Li GH, Chen W, Arakaki C, Botimer GD, Baylink D, Zhang L, Wen W, Fu YW, Xu J, Chun N, Yuan W, Cheng T, Zhang XB. Zhang JP, et al. Among authors: wen w. Genome Biol. 2017 Feb 20;18(1):35. doi: 10.1186/s13059-017-1164-8. Genome Biol. 2017. PMID: 28219395 Free PMC article.

6

High-Level Precise Knockin of iPSCs by Simultaneous Reprogramming and Genome Editing of Human Peripheral Blood Mononuclear Cells.

Wen W, Cheng X, Fu Y, Meng F, Zhang JP, Zhang L, Li XL, Yang Z, Xu J, Zhang F, Botimer GD, Yuan W, Sun C, Cheng T, Zhang XB. Wen W, et al. Stem Cell Reports. 2018 Jun 5;10(6):1821-1834. doi: 10.1016/j.stemcr.2018.04.013. Epub 2018 May 10. Stem Cell Reports. 2018. PMID: 29754960 Free PMC article.

7

Highly efficient genome editing via CRISPR-Cas9 in human pluripotent stem cells is achieved by transient BCL-XL overexpression.

Li XL, Li GH, Fu J, Fu YW, Zhang L, Chen W, Arakaki C, Zhang JP, Wen W, Zhao M, Chen WV, Botimer GD, Baylink D, Aranda L, Choi H, Bechar R, Talbot P, Sun CK, Cheng T, Zhang XB. Li XL, et al. Among authors: wen w. Nucleic Acids Res. 2018 Nov 2;46(19):10195-10215. doi: 10.1093/nar/gky804. Nucleic Acids Res. 2018. PMID: 30239926 Free PMC article.

8

Curing hemophilia A by NHEJ-mediated ectopic F8 insertion in the mouse.

Zhang JP, Cheng XX, Zhao M, Li GH, Xu J, Zhang F, Yin MD, Meng FY, Dai XY, Fu YW, Yang ZX, Arakaki C, Su RJ, Wen W, Wang WT, Chen W, Choi H, Wang C, Gao G, Zhang L, Cheng T, Zhang XB. Zhang JP, et al. Among authors: wen w. Genome Biol. 2019 Dec 16;20(1):276. doi: 10.1186/s13059-019-1907-9. Genome Biol. 2019. PMID: 31843008 Free PMC article.

9

Episomal Reprogramming of Human Peripheral Blood Mononuclear Cells into Pluripotency.

Wen W, Cheng T, Zhang XB. Wen W, et al. Methods Mol Biol. 2021;2239:117-133. doi: 10.1007/978-1-0716-1084-8_8. Methods Mol Biol. 2021. PMID: 33226616

10

Dynamics and competition of CRISPR-Cas9 ribonucleoproteins and AAV donor-mediated NHEJ, MMEJ and HDR editing.

Fu YW, Dai XY, Wang WT, Yang ZX, Zhao JJ, Zhang JP, Wen W, Zhang F, Oberg KC, Zhang L, Cheng T, Zhang XB. Fu YW, et al. Among authors: wen w. Nucleic Acids Res. 2021 Jan 25;49(2):969-985. doi: 10.1093/nar/gkaa1251. Nucleic Acids Res. 2021. PMID: 33398341 Free PMC article.

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