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Voltage tunes mGlu5 receptor function, impacting synaptic transmission.
Boutonnet M, Carpena C, Bouquier N, Chastagnier Y, Font-Ingles J, Moutin E, Tricoire L, Chemin J, Perroy J. Boutonnet M, et al. Among authors: tricoire l. Br J Pharmacol. 2024 Jun;181(12):1793-1811. doi: 10.1111/bph.16317. Epub 2024 Feb 18. Br J Pharmacol. 2024. PMID: 38369690
GRID1/GluD1 homozygous variants linked to intellectual disability and spastic paraplegia impair mGlu1/5 receptor signaling and excitatory synapses.
Ung DC, Pietrancosta N, Badillo EB, Raux B, Tapken D, Zlatanovic A, Doridant A, Pode-Shakked B, Raas-Rothschild A, Elpeleg O, Abu-Libdeh B, Hamed N, Papon MA, Marouillat S, Thépault RA, Stevanin G, Elegheert J, Letellier M, Hollmann M, Lambolez B, Tricoire L, Toutain A, Hepp R, Laumonnier F. Ung DC, et al. Among authors: tricoire l. Mol Psychiatry. 2024 Apr;29(4):1205-1215. doi: 10.1038/s41380-024-02469-w. Epub 2024 Feb 28. Mol Psychiatry. 2024. PMID: 38418578 Free PMC article.
40 results