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Synthetic repertoires derived from convalescent COVID-19 patients enable discovery of SARS-CoV-2 neutralizing antibodies and a novel quaternary binding modality.
Goike J, Hsieh CL, Horton A, Gardner EC, Bartzoka F, Wang N, Javanmardi K, Herbert A, Abbassi S, Renberg R, Johanson MJ, Cardona JA, Segall-Shapiro T, Zhou L, Nissly RH, Gontu A, Byrom M, Maranhao AC, Battenhouse AM, Gejji V, Soto-Sierra L, Foster ER, Woodard SL, Nikolov ZL, Lavinder J, Voss WN, Annapareddy A, Ippolito GC, Ellington AD, Marcotte EM, Finkelstein IJ, Hughes RA, Musser JM, Kuchipudi SV, Kapur V, Georgiou G, Dye JM, Boutz DR, McLellan JS, Gollihar JD. Goike J, et al. Among authors: zhou l. bioRxiv [Preprint]. 2021 Apr 9:2021.04.07.438849. doi: 10.1101/2021.04.07.438849. bioRxiv. 2021. PMID: 33851158 Free PMC article. Preprint.
Simulation-driven design of stabilized SARS-CoV-2 spike S2 immunogens.
Nuqui X, Casalino L, Zhou L, Shehata M, Wang A, Tse AL, Ojha AA, Kearns FL, Rosenfeld MA, Miller EH, Acreman CM, Ahn SH, Chandran K, McLellan JS, Amaro RE. Nuqui X, et al. Among authors: zhou l. Nat Commun. 2024 Aug 27;15(1):7370. doi: 10.1038/s41467-024-50976-9. Nat Commun. 2024. PMID: 39191724 Free PMC article.
Structure-based design of a soluble human cytomegalovirus glycoprotein B antigen stabilized in a prefusion-like conformation.
Sponholtz MR, Byrne PO, Lee AG, Ramamohan AR, Goldsmith JA, McCool RS, Zhou L, Johnson NV, Hsieh CL, Connors M, Karthigeyan KP, Crooks CM, Fuller AS, Campbell JD, Permar SR, Maynard JA, Yu D, Bottomley MJ, McLellan JS. Sponholtz MR, et al. Among authors: zhou l. Proc Natl Acad Sci U S A. 2024 Sep 10;121(37):e2404250121. doi: 10.1073/pnas.2404250121. Epub 2024 Sep 4. Proc Natl Acad Sci U S A. 2024. PMID: 39231203 Free PMC article.
33,263 results
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