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Page 1
Targeted protein degradation via intramolecular bivalent glues.
Hsia O, Hinterndorfer M, Cowan AD, Iso K, Ishida T, Sundaramoorthy R, Nakasone MA, Imrichova H, Schätz C, Rukavina A, Husnjak K, Wegner M, Correa-Sáez A, Craigon C, Casement R, Maniaci C, Testa A, Kaulich M, Dikic I, Winter GE, Ciulli A. Hsia O, et al. Among authors: rukavina a. Nature. 2024 Mar;627(8002):204-211. doi: 10.1038/s41586-024-07089-6. Epub 2024 Feb 21. Nature. 2024. PMID: 38383787 Free PMC article.
Paralog-dependent isogenic cell assay cascade generates highly selective SLC16A3 inhibitors.
Dvorak V, Casiraghi A, Colas C, Koren A, Tomek T, Offensperger F, Rukavina A, Tin G, Hahn E, Dobner S, Frommelt F, Boeszoermenyi A, Bernada V, Hannich JT, Ecker GF, Winter GE, Kubicek S, Superti-Furga G. Dvorak V, et al. Among authors: rukavina a. Cell Chem Biol. 2023 Aug 17;30(8):953-964.e9. doi: 10.1016/j.chembiol.2023.06.029. Epub 2023 Jul 28. Cell Chem Biol. 2023. PMID: 37516113 Free PMC article.
Pharmacological perturbation of the phase-separating protein SMNDC1.
Enders L, Siklos M, Borggräfe J, Gaussmann S, Koren A, Malik M, Tomek T, Schuster M, Reiniš J, Hahn E, Rukavina A, Reicher A, Casteels T, Bock C, Winter GE, Hannich JT, Sattler M, Kubicek S. Enders L, et al. Among authors: rukavina a. Nat Commun. 2023 Aug 16;14(1):4504. doi: 10.1038/s41467-023-40124-0. Nat Commun. 2023. PMID: 37587144 Free PMC article.
Discovery of Molecular Glue Degraders via Isogenic Morphological Profiling.
Ng A, Offensperger F, Cisneros JA, Scholes NS, Malik M, Villanti L, Rukavina A, Ferrada E, Hannich JT, Koren A, Kubicek S, Superti-Furga G, Winter GE. Ng A, et al. Among authors: rukavina a. ACS Chem Biol. 2023 Dec 15;18(12):2464-2473. doi: 10.1021/acschembio.3c00598. Epub 2023 Nov 21. ACS Chem Biol. 2023. PMID: 38098458 Free PMC article.
Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells.
Offensperger F, Tin G, Duran-Frigola M, Hahn E, Dobner S, Ende CWA, Strohbach JW, Rukavina A, Brennsteiner V, Ogilvie K, Marella N, Kladnik K, Ciuffa R, Majmudar JD, Field SD, Bensimon A, Ferrari L, Ferrada E, Ng A, Zhang Z, Degliesposti G, Boeszoermenyi A, Martens S, Stanton R, Müller AC, Hannich JT, Hepworth D, Superti-Furga G, Kubicek S, Schenone M, Winter GE. Offensperger F, et al. Among authors: rukavina a. Science. 2024 Apr 26;384(6694):eadk5864. doi: 10.1126/science.adk5864. Epub 2024 Apr 26. Science. 2024. PMID: 38662832
Orpinolide disrupts a leukemic dependency on cholesterol transport by inhibiting OSBP.
Cigler M, Imrichova H, Frommelt F, Caramelle L, Depta L, Rukavina A, Kagiou C, Hannich JT, Mayor-Ruiz C, Superti-Furga G, Sievers S, Forrester A, Laraia L, Waldmann H, Winter GE. Cigler M, et al. Among authors: rukavina a. Nat Chem Biol. 2024 Jun 21. doi: 10.1038/s41589-024-01614-4. Online ahead of print. Nat Chem Biol. 2024. PMID: 38907113
Psychogeriatric Diagnoses in Old People's Homes and Negative Health Behavior.
Tomek-Roksandić S, Popek I, Mrčela NT, Šostar Z, Kolarić B, Narančić NS, Rukavina AS, Ljubičić M. Tomek-Roksandić S, et al. Among authors: rukavina as. Psychiatr Danub. 2017 Sep;29(3):369-375. doi: 10.24869/psyd.2017.369. Psychiatr Danub. 2017. PMID: 28949318 Free article.
Recurrent hemarthrosis after total knee arthroplasty.
Rukavina A, Kerkhoffs GM, Schneider P, Kuster MS. Rukavina A, et al. Knee Surg Sports Traumatol Arthrosc. 2010 Jul;18(7):898-900. doi: 10.1007/s00167-009-1031-6. Epub 2010 Jan 14. Knee Surg Sports Traumatol Arthrosc. 2010. PMID: 20076944 Free PMC article.
31 results