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Targeted protein degradation via intramolecular bivalent glues.
Hsia O, Hinterndorfer M, Cowan AD, Iso K, Ishida T, Sundaramoorthy R, Nakasone MA, Imrichova H, Schätz C, Rukavina A, Husnjak K, Wegner M, Correa-Sáez A, Craigon C, Casement R, Maniaci C, Testa A, Kaulich M, Dikic I, Winter GE, Ciulli A. Hsia O, et al. Among authors: wegner m. Nature. 2024 Mar;627(8002):204-211. doi: 10.1038/s41586-024-07089-6. Epub 2024 Feb 21. Nature. 2024. PMID: 38383787 Free PMC article.
Minimized combinatorial CRISPR screens identify genetic interactions in autophagy.
Diehl V, Wegner M, Grumati P, Husnjak K, Schaubeck S, Gubas A, Shah VJ, Polat IH, Langschied F, Prieto-Garcia C, Müller K, Kalousi A, Ebersberger I, Brandts CH, Dikic I, Kaulich M. Diehl V, et al. Among authors: wegner m. Nucleic Acids Res. 2021 Jun 4;49(10):5684-5704. doi: 10.1093/nar/gkab309. Nucleic Acids Res. 2021. PMID: 33956155 Free PMC article.
Optimized metrics for orthogonal combinatorial CRISPR screens.
Cetin R, Wegner M, Luwisch L, Saud S, Achmedov T, Süsser S, Vera-Guapi A, Müller K, Matthess Y, Quandt E, Schaubeck S, Beisel CL, Kaulich M. Cetin R, et al. Among authors: wegner m. Sci Rep. 2023 May 6;13(1):7405. doi: 10.1038/s41598-023-34597-8. Sci Rep. 2023. PMID: 37149686 Free PMC article.
499 results