Rocha S - Search Results

1

Melanoxetin: A Hydroxylated Flavonoid Attenuates Oxidative Stress and Modulates Insulin Resistance and Glycation Pathways in an Animal Model of Type 2 Diabetes Mellitus.

Rocha S, Amaro A, Ferreira-Junior MD, Proença C, Silva AMS, Costa VM, Oliveira S, Fonseca DA, Silva S, Corvo ML, Freitas M, Matafome P, Fernandes E. Rocha S, et al. Pharmaceutics. 2024 Feb 9;16(2):261. doi: 10.3390/pharmaceutics16020261. Pharmaceutics. 2024. PMID: 38399315 Free PMC article.

2

A Systematic Review on Anti-diabetic Properties of Chalcones.

Rocha S, Ribeiro D, Fernandes E, Freitas M. Rocha S, et al. Curr Med Chem. 2020;27(14):2257-2321. doi: 10.2174/0929867325666181001112226. Curr Med Chem. 2020. PMID: 30277140

3

A study towards drug discovery for the management of type 2 diabetes mellitus through inhibition of the carbohydrate-hydrolyzing enzymes α-amylase and α-glucosidase by chalcone derivatives.

Rocha S, Sousa A, Ribeiro D, Correia CM, Silva VLM, Santos CMM, Silva AMS, Araújo AN, Fernandes E, Freitas M. Rocha S, et al. Food Funct. 2019 Sep 1;10(9):5510-5520. doi: 10.1039/c9fo01298b. Epub 2019 Aug 15. Food Funct. 2019. PMID: 31414099

4

Correction: A study towards drug discovery for the management of type 2 diabetes mellitus through inhibition of the carbohydrate-hydrolyzing enzymes α-amylase and α-glucosidase by chalcone derivatives.

Rocha S, Sousa A, Ribeiro D, Correia CM, Silva VLM, Santos CMM, Silva AMS, Araújo AN, Fernandes E, Freitas M. Rocha S, et al. Food Funct. 2019 Sep 1;10(9):6203. doi: 10.1039/c9fo90045d. Epub 2019 Aug 27. Food Funct. 2019. PMID: 31454004

5

Nano-based drug delivery systems used as vehicles to enhance polyphenols therapeutic effect for diabetes mellitus treatment.

Rocha S, Lucas M, Ribeiro D, Corvo ML, Fernandes E, Freitas M. Rocha S, et al. Pharmacol Res. 2021 Jul;169:105604. doi: 10.1016/j.phrs.2021.105604. Epub 2021 May 4. Pharmacol Res. 2021. PMID: 33845125 Review.

6

Pyrazoles as novel protein tyrosine phosphatase 1B (PTP1B) inhibitors: An in vitro and in silico study.

Rocha S, Lucas M, Silva VLM, Gomes PMO, Silva AMS, Araújo AN, Aniceto N, Guedes RC, Corvo ML, Fernandes E, Freitas M. Rocha S, et al. Int J Biol Macromol. 2021 Jun 30;181:1171-1182. doi: 10.1016/j.ijbiomac.2021.04.061. Epub 2021 Apr 13. Int J Biol Macromol. 2021. PMID: 33857515

7

Optimization and Validation of an In Vitro Standardized Glycogen Phosphorylase Activity Assay.

Rocha S, Lucas M, Araújo AN, Corvo ML, Fernandes E, Freitas M. Rocha S, et al. Molecules. 2021 Jul 30;26(15):4635. doi: 10.3390/molecules26154635. Molecules. 2021. PMID: 34361792 Free PMC article.

8

An In Silico and an In Vitro Inhibition Analysis of Glycogen Phosphorylase by Flavonoids, Styrylchromones, and Pyrazoles.

Rocha S, Aniceto N, Guedes RC, Albuquerque HMT, Silva VLM, Silva AMS, Corvo ML, Fernandes E, Freitas M. Rocha S, et al. Nutrients. 2022 Jan 12;14(2):306. doi: 10.3390/nu14020306. Nutrients. 2022. PMID: 35057487 Free PMC article.

9

Pyrazoles have a multifaceted anti-inflammatory effect targeting prostaglandin E₂, cyclooxygenases and leukocytes' oxidative burst.

Rocha S, Silva J, Silva VLM, Silva AMS, Corvo ML, Freitas M, Fernandes E. Rocha S, et al. Int J Biochem Cell Biol. 2024 Jul;172:106599. doi: 10.1016/j.biocel.2024.106599. Epub 2024 May 24. Int J Biochem Cell Biol. 2024. PMID: 38797495 Free article.

10

Liposomal quercetin: A promising strategy to combat hepatic insulin resistance and inflammation in type 2 diabetes mellitus.

Rocha S, Luísa Corvo M, Freitas M, Fernandes E. Rocha S, et al. Int J Pharm. 2024 Aug 15;661:124441. doi: 10.1016/j.ijpharm.2024.124441. Epub 2024 Jul 6. Int J Pharm. 2024. PMID: 38977164 Free article.

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