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DUSP6 inhibition overcomes neuregulin/HER3-driven therapy tolerance in HER2+ breast cancer.
Momeny M, Tienhaara M, Sharma M, Chakroborty D, Varjus R, Takala I, Merisaari J, Padzik A, Vogt A, Paatero I, Elenius K, Laajala TD, Kurppa KJ, Westermarck J. Momeny M, et al. Among authors: laajala td. EMBO Mol Med. 2024 Jul;16(7):1603-1629. doi: 10.1038/s44321-024-00088-0. Epub 2024 Jun 17. EMBO Mol Med. 2024. PMID: 38886591 Free PMC article.
NPEPPS Is a Druggable Driver of Platinum Resistance.
Jones RT, Scholtes M, Goodspeed A, Akbarzadeh M, Mohapatra S, Feldman LE, Vekony H, Jean A, Tilton CB, Orman MV, Romal S, Deiter C, Kan TW, Xander N, Araki SP, Joshi M, Javaid M, Clambey ET, Layer R, Laajala TD, Parker SJ, Mahmoudi T, Zuiverloon TCM, Theodorescu D, Costello JC. Jones RT, et al. Among authors: laajala td. Cancer Res. 2024 May 15;84(10):1699-1718. doi: 10.1158/0008-5472.CAN-23-1976. Cancer Res. 2024. PMID: 38535994 Free PMC article.
A community challenge to predict clinical outcomes after immune checkpoint blockade in non-small cell lung cancer.
Mason M, Lapuente-Santana Ó, Halkola AS, Wang W, Mall R, Xiao X, Kaufman J, Fu J, Pfeil J, Banerjee J, Chung V, Chang H, Chasalow SD, Lin HY, Chai R, Yu T, Finotello F, Mirtti T, Mäyränpää MI, Bao J, Verschuren EW, Ahmed EI, Ceccarelli M, Miller LD, Monaco G, Hendrickx WRL, Sherif S, Yang L, Tang M, Gu SS, Zhang W, Zhang Y, Zeng Z, Das Sahu A, Liu Y, Yang W, Bedognetti D, Tang J, Eduati F, Laajala TD, Geese WJ, Guinney J, Szustakowski JD, Vincent BG, Carbone DP. Mason M, et al. Among authors: laajala td. J Transl Med. 2024 Feb 21;22(1):190. doi: 10.1186/s12967-023-04705-3. J Transl Med. 2024. PMID: 38383458 Free PMC article.
MRI-Targeted Prostate Biopsy Introduces Grade Inflation and Overtreatment.
Batouche AO, Czeizler E, Lehto TP, Erickson A, Shadbahr T, Laajala TD, Pohjonen J, Vickers AJ, Mirtti T, Rannikko AS. Batouche AO, et al. Among authors: laajala td. medRxiv [Preprint]. 2024 Jan 10:2024.01.10.24300922. doi: 10.1101/2024.01.10.24300922. medRxiv. 2024. PMID: 38260466 Free PMC article. Preprint.
Microbiome-based risk prediction in incident heart failure: a community challenge.
Erawijantari PP, Kartal E, Liñares-Blanco J, Laajala TD, Feldman LE; FINRISK Microbiome DREAM Challenge and ML4Microbiome Communities; Carmona-Saez P, Shigdel R, Claesson MJ, Bertelsen RJ, Gomez-Cabrero D, Minot S, Albrecht J, Chung V, Inouye M, Jousilahti P, Schultz JH, Friederich HC, Knight R, Salomaa V, Niiranen T, Havulinna AS, Saez-Rodriguez J, Levinson RT, Lahti L. Erawijantari PP, et al. Among authors: laajala td. medRxiv [Preprint]. 2023 Oct 12:2023.10.12.23296829. doi: 10.1101/2023.10.12.23296829. medRxiv. 2023. PMID: 37873403 Free PMC article. Preprint.
The Effect of a Fish Oil and/or Probiotic Intervention from Early Pregnancy Onwards on Colostrum Immune Mediators: A Randomized, Placebo-Controlled, Double-Blinded Clinical Trial in Overweight/Obese Mothers.
Soukka J, Polari L, Kalliomäki M, Saros L, Laajala TD, Vahlberg T, Toivola DM, Laitinen K. Soukka J, et al. Among authors: laajala td. Mol Nutr Food Res. 2023 Aug;67(15):e2200446. doi: 10.1002/mnfr.202200446. Epub 2023 Jun 16. Mol Nutr Food Res. 2023. PMID: 37326413 Clinical Trial.
Non-muscle-invasive bladder cancer molecular subtypes predict differential response to intravesical Bacillus Calmette-Guérin.
de Jong FC, Laajala TD, Hoedemaeker RF, Jordan KR, van der Made ACJ, Boevé ER, van der Schoot DKE, Nieuwkamer B, Janssen EAM, Mahmoudi T, Boormans JL, Theodorescu D, Costello JC, Zuiverloon TCM. de Jong FC, et al. Among authors: laajala td. Sci Transl Med. 2023 May 24;15(697):eabn4118. doi: 10.1126/scitranslmed.abn4118. Epub 2023 May 24. Sci Transl Med. 2023. PMID: 37224225 Free PMC article.
51 results