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Page 1
Dietary pro-oxidant therapy by a vitamin K precursor targets PI 3-kinase VPS34 function.
Swamynathan MM, Kuang S, Watrud KE, Doherty MR, Gineste C, Mathew G, Gong GQ, Cox H, Cheng E, Reiss D, Kendall J, Ghosh D, Reczek CR, Zhao X, Herzka T, Špokaitė S, Dessus AN, Kim ST, Klingbeil O, Liu J, Nowak DG, Alsudani H, Wee TL, Park Y, Minicozzi F, Rivera K, Almeida AS, Chang K, Chakrabarty RP, Wilkinson JE, Gimotty PA, Diermeier SD, Egeblad M, Vakoc CR, Locasale JW, Chandel NS, Janowitz T, Hicks JB, Wigler M, Pappin DJ, Williams RL, Cifani P, Tuveson DA, Laporte J, Trotman LC. Swamynathan MM, et al. Among authors: janowitz t. Science. 2024 Oct 25;386(6720):eadk9167. doi: 10.1126/science.adk9167. Epub 2024 Oct 25. Science. 2024. PMID: 39446948
Why do patients with cancer die?
Boire A, Burke K, Cox TR, Guise T, Jamal-Hanjani M, Janowitz T, Kaplan R, Lee R, Swanton C, Vander Heiden MG, Sahai E. Boire A, et al. Among authors: janowitz t. Nat Rev Cancer. 2024 Aug;24(8):578-589. doi: 10.1038/s41568-024-00708-4. Epub 2024 Jun 19. Nat Rev Cancer. 2024. PMID: 38898221 Free PMC article. Review.
Area postrema neurons mediate interleukin-6 function in cancer cachexia.
Sun Q, van de Lisdonk D, Ferrer M, Gegenhuber B, Wu M, Park Y, Tuveson DA, Tollkuhn J, Janowitz T, Li B. Sun Q, et al. Among authors: janowitz t. Nat Commun. 2024 Jun 1;15(1):4682. doi: 10.1038/s41467-024-48971-1. Nat Commun. 2024. PMID: 38824130 Free PMC article.
Restoring adiponectin via rosiglitazone ameliorates tissue wasting in mice with lung cancer.
Langer HT, Ramsamooj S, Dantas E, Murthy A, Ahmed M, Ahmed T, Hwang SK, Grover R, Pozovskiy R, Liang RJ, Queiroz AL, Brown JC, White EP, Janowitz T, Goncalves MD. Langer HT, et al. Among authors: janowitz t. Acta Physiol (Oxf). 2024 Aug;240(8):e14167. doi: 10.1111/apha.14167. Epub 2024 May 23. Acta Physiol (Oxf). 2024. PMID: 38779820
A guideline on the molecular ecosystem regulating ferroptosis.
Dai E, Chen X, Linkermann A, Jiang X, Kang R, Kagan VE, Bayir H, Yang WS, Garcia-Saez AJ, Ioannou MS, Janowitz T, Ran Q, Gu W, Gan B, Krysko DV, Zhu X, Wang J, Krautwald S, Toyokuni S, Xie Y, Greten FR, Yi Q, Schick J, Liu J, Gabrilovich DI, Liu J, Zeh HJ, Zhang DD, Yang M, Iovanna J, Kopf M, Adolph TE, Chi JT, Li C, Ichijo H, Karin M, Sankaran VG, Zou W, Galluzzi L, Bush AI, Li B, Melino G, Baehrecke EH, Lotze MT, Klionsky DJ, Stockwell BR, Kroemer G, Tang D. Dai E, et al. Among authors: janowitz t. Nat Cell Biol. 2024 Sep;26(9):1447-1457. doi: 10.1038/s41556-024-01360-8. Epub 2024 Feb 29. Nat Cell Biol. 2024. PMID: 38424270 Review.
Opportunities and challenges for innovative and equitable healthcare.
Ecker DJ, Aiello CD, Arron JR, Bennett CF, Bernard A, Breakefield XO, Broderick TJ, Callier SL, Canton B, Chen JS, Fishburn CS, Garrett B, Hecht SM, Janowitz T, Kliegman M, Krainer A, Louis CU, Lowe C, Sehgal A, Tozan Y, Tracey KJ, Urnov F, Wattendorf D, Williams TW, Zhao X, Hayden MR. Ecker DJ, et al. Among authors: janowitz t. Nat Rev Drug Discov. 2024 May;23(5):321-322. doi: 10.1038/d41573-024-00032-4. Nat Rev Drug Discov. 2024. PMID: 38409339 No abstract available.
Cystatin C is glucocorticoid responsive, directs recruitment of Trem2+ macrophages, and predicts failure of cancer immunotherapy.
Kleeman SO, Thakir TM, Demestichas B, Mourikis N, Loiero D, Ferrer M, Bankier S, Riazat-Kesh YJRA, Lee H, Chantzichristos D, Regan C, Preall J, Sinha S, Rosin N, Yipp B, de Almeida LGN, Biernaskie J, Dufour A, Tober-Lau P, Ruusalepp A, Bjorkegren JLM, Ralser M, Kurth F, Demichev V, Heywood T, Gao Q, Johannsson G, Koelzer VH, Walker BR, Meyer HV, Janowitz T. Kleeman SO, et al. Among authors: janowitz t. Cell Genom. 2023 Jun 23;3(8):100347. doi: 10.1016/j.xgen.2023.100347. eCollection 2023 Aug 9. Cell Genom. 2023. PMID: 37601967 Free PMC article.
72 results