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234 results

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Page 1
Aldehydes alter TGF-β signaling and induce obesity and cancer.
Yang X, Bhowmick K, Rao S, Xiang X, Ohshiro K, Amdur RL, Hassan MI, Mohammad T, Crandall K, Cifani P, Shetty K, Lyons SK, Merrill JR, Vegesna AK, John S, Latham PS, Crawford JM, Mishra B, Dasarathy S, Wang XW, Yu H, Wang Z, Huang H, Krainer AR, Mishra L. Yang X, et al. Among authors: krainer ar. Cell Rep. 2024 Sep 24;43(9):114676. doi: 10.1016/j.celrep.2024.114676. Epub 2024 Aug 31. Cell Rep. 2024. PMID: 39217614 Free PMC article.
Interaction between MED12 and ΔNp63 activates basal identity in pancreatic ductal adenocarcinoma.
Maia-Silva D, Cunniff PJ, Schier AC, Skopelitis D, Trousdell MC, Moresco P, Gao Y, Kechejian V, He XY, Sahin Y, Wan L, Alpsoy A, Liverpool J, Krainer AR, Egeblad M, Spector DL, Fearon DT, Dos Santos CO, Taatjes DJ, Vakoc CR. Maia-Silva D, et al. Among authors: krainer ar. Nat Genet. 2024 Jul;56(7):1377-1385. doi: 10.1038/s41588-024-01790-y. Epub 2024 Jun 17. Nat Genet. 2024. PMID: 38886586
Specificity, synergy, and mechanisms of splice-modifying drugs.
Ishigami Y, Wong MS, Martí-Gómez C, Ayaz A, Kooshkbaghi M, Hanson SM, McCandlish DM, Krainer AR, Kinney JB. Ishigami Y, et al. Among authors: krainer ar. Nat Commun. 2024 Feb 29;15(1):1880. doi: 10.1038/s41467-024-46090-5. Nat Commun. 2024. PMID: 38424098 Free PMC article.
Opportunities and challenges for innovative and equitable healthcare.
Ecker DJ, Aiello CD, Arron JR, Bennett CF, Bernard A, Breakefield XO, Broderick TJ, Callier SL, Canton B, Chen JS, Fishburn CS, Garrett B, Hecht SM, Janowitz T, Kliegman M, Krainer A, Louis CU, Lowe C, Sehgal A, Tozan Y, Tracey KJ, Urnov F, Wattendorf D, Williams TW, Zhao X, Hayden MR. Ecker DJ, et al. Among authors: krainer a. Nat Rev Drug Discov. 2024 May;23(5):321-322. doi: 10.1038/d41573-024-00032-4. Nat Rev Drug Discov. 2024. PMID: 38409339 No abstract available.
Mechanistically based blood proteomic markers in the TGF-β pathway stratify risk of hepatocellular cancer in patients with cirrhosis.
Xiang X, Bhowmick K, Shetty K, Ohshiro K, Yang X, Wong LL, Yu H, Latham PS, Satapathy SK, Brennan C, Dima RJ, Chambwe N, Sharifova G, Cacaj F, John S, Crawford JM, Huang H, Dasarathy S, Krainer AR, He AR, Amdur RL, Mishra L. Xiang X, et al. Among authors: krainer ar. Genes Cancer. 2024 Feb 1;15:1-14. doi: 10.18632/genesandcancer.234. eCollection 2024. Genes Cancer. 2024. PMID: 38323119 Free PMC article.
Antisense oligonucleotide therapy for H3.3K27M diffuse midline glioma.
Zhang Q, Yang L, Liu YH, Wilkinson JE, Krainer AR. Zhang Q, et al. Among authors: krainer ar. Sci Transl Med. 2023 Apr 12;15(691):eadd8280. doi: 10.1126/scitranslmed.add8280. Epub 2023 Apr 12. Sci Transl Med. 2023. PMID: 37043556 Free PMC article.
234 results