Kohler ME - Search Results

1

Granzyme F: Exhaustion Marker and Modulator of Chimeric Antigen Receptor T Cell-Mediated Cytotoxicity.

Hay ZLZ, Kim DD, Cimons JM, Knapp JR, Kohler ME, Quansah M, Zúñiga TM, Camp FA, Fujita M, Wang XJ, O'Connor BP, Slansky JE. Hay ZLZ, et al. Among authors: kohler me. J Immunol. 2024 Apr 15;212(8):1381-1391. doi: 10.4049/jimmunol.2300334. J Immunol. 2024. PMID: 38416029

2

Antigen experience history directs distinct functional states of CD8+ CAR T cells during the anti-leukemia response.

DeGolier KR, Danis E, D'Antonio M, Cimons J, Yarnell M, Kedl RM, Kohler ME, Scott-Browne JP, Fry TJ. DeGolier KR, et al. Among authors: kohler me. Res Sq [Preprint]. 2023 Dec 21:rs.3.rs-3712137. doi: 10.21203/rs.3.rs-3712137/v1. Res Sq. 2023. PMID: 38196657 Free PMC article. Preprint.

3

Deleting the mitochondrial respiration negative regulator MCJ enhances the efficacy of CD8⁺ T cell adoptive therapies in pre-clinical studies.

Wu MH, Valenca-Pereira F, Cendali F, Giddings EL, Pham-Danis C, Yarnell MC, Novak AJ, Brunetti TM, Thompson SB, Henao-Mejia J, Flavell RA, D'Alessandro A, Kohler ME, Rincon M. Wu MH, et al. Among authors: kohler me. Nat Commun. 2024 May 24;15(1):4444. doi: 10.1038/s41467-024-48653-y. Nat Commun. 2024. PMID: 38789421 Free PMC article.

4

Immunobiology of chimeric antigen receptor T cells and novel designs.

Walsh Z, Yang Y, Kohler ME. Walsh Z, et al. Among authors: kohler me. Immunol Rev. 2019 Jul;290(1):100-113. doi: 10.1111/imr.12794. Immunol Rev. 2019. PMID: 31355496 Review.

5

Potent preclinical activity of FLT3-directed chimeric antigen receptor T-cell immunotherapy against FLT3- mutant acute myeloid leukemia and KMT2A-rearranged acute lymphoblastic leukemia.

Niswander LM, Graff ZT, Chien CD, Chukinas JA, Meadows CA, Leach LC, Loftus JP, Kohler ME, Tasian SK, Fry TJ. Niswander LM, et al. Among authors: kohler me. Haematologica. 2023 Feb 1;108(2):457-471. doi: 10.3324/haematol.2022.281456. Haematologica. 2023. PMID: 35950535 Free PMC article.

6

Outcomes of Critically Ill Children With Acute Lymphoblastic Leukemia and Cytokine Release Syndrome Due to Chimeric Antigen Receptor T Cell Therapy: US, Multicenter PICU, Cohort Database Study.

Logan GE, Miller K, Kohler ME, Loi M, Maddux AB. Logan GE, et al. Among authors: kohler me. Pediatr Crit Care Med. 2022 Dec 1;23(12):e595-e600. doi: 10.1097/PCC.0000000000003079. Epub 2022 Oct 4. Pediatr Crit Care Med. 2022. PMID: 36194016 Free PMC article.

7

Digital polymerase chain reaction strategies for accurate and precise detection of vector copy number in chimeric antigen receptor T-cell products.

Murphy LA, Marians RC, Miller K, Brenton MD, Mallo RLV, Kohler ME, Fry TJ, Winters AC. Murphy LA, et al. Among authors: kohler me. Cytotherapy. 2023 Jan;25(1):94-102. doi: 10.1016/j.jcyt.2022.09.004. Epub 2022 Oct 14. Cytotherapy. 2023. PMID: 36253252 Free PMC article.

8

4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors.

Long AH, Haso WM, Shern JF, Wanhainen KM, Murgai M, Ingaramo M, Smith JP, Walker AJ, Kohler ME, Venkateshwara VR, Kaplan RN, Patterson GH, Fry TJ, Orentas RJ, Mackall CL. Long AH, et al. Among authors: kohler me. Nat Med. 2015 Jun;21(6):581-90. doi: 10.1038/nm.3838. Epub 2015 May 4. Nat Med. 2015. PMID: 25939063 Free PMC article.

9

Does lineage plasticity enable escape from CAR-T cell therapy? Lessons from MLL-r leukemia.

Liao W, Kohler ME, Fry T, Ernst P. Liao W, et al. Among authors: kohler me. Exp Hematol. 2021 Aug;100:1-11. doi: 10.1016/j.exphem.2021.07.002. Epub 2021 Jul 21. Exp Hematol. 2021. PMID: 34298117 Free PMC article. Review.

10

Corrigendum to <Does lineage plasticity enable escape from CAR-T cell therapy? Lessons from MLL-r leukemia'>: <[Experimental Hematology 2021; 100: 1-11]>

Liao W, Kohler ME, Fry T, Ernst P. Liao W, et al. Among authors: kohler me. Exp Hematol. 2021 Nov;103:73-74. doi: 10.1016/j.exphem.2021.09.002. Epub 2021 Sep 21. Exp Hematol. 2021. PMID: 34555335 Free article. No abstract available.

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