Galetin A - Search Results

1

Facing the Facts of Altered Plasma Protein Binding: Do Current Models Correctly Predict Changes in Fraction Unbound in Special Populations?

Al-Qassabi J, Tan SPF, Phonboon P, Galetin A, Rostami-Hodjegan A, Scotcher D. Al-Qassabi J, et al. Among authors: galetin a. J Pharm Sci. 2024 Jun;113(6):1664-1673. doi: 10.1016/j.xphs.2024.02.024. Epub 2024 Feb 28. J Pharm Sci. 2024. PMID: 38417790 Free article.

2

Human udp-glucuronosyltransferases: isoform selectivity and kinetics of 4-methylumbelliferone and 1-naphthol glucuronidation, effects of organic solvents, and inhibition by diclofenac and probenecid.

Uchaipichat V, Mackenzie PI, Guo XH, Gardner-Stephen D, Galetin A, Houston JB, Miners JO. Uchaipichat V, et al. Among authors: galetin a. Drug Metab Dispos. 2004 Apr;32(4):413-23. doi: 10.1124/dmd.32.4.413. Drug Metab Dispos. 2004. PMID: 15039294

3

Critique of the two-fold measure of prediction success for ratios: application for the assessment of drug-drug interactions.

Guest EJ, Aarons L, Houston JB, Rostami-Hodjegan A, Galetin A. Guest EJ, et al. Among authors: galetin a. Drug Metab Dispos. 2011 Feb;39(2):170-3. doi: 10.1124/dmd.110.036103. Epub 2010 Oct 29. Drug Metab Dispos. 2011. PMID: 21036951

4

Assessment of algorithms for predicting drug-drug interactions via inhibition mechanisms: comparison of dynamic and static models.

Guest EJ, Rowland-Yeo K, Rostami-Hodjegan A, Tucker GT, Houston JB, Galetin A. Guest EJ, et al. Among authors: galetin a. Br J Clin Pharmacol. 2011 Jan;71(1):72-87. doi: 10.1111/j.1365-2125.2010.03799.x. Br J Clin Pharmacol. 2011. PMID: 21143503 Free PMC article.

5

PBPK models for the prediction of in vivo performance of oral dosage forms.

Kostewicz ES, Aarons L, Bergstrand M, Bolger MB, Galetin A, Hatley O, Jamei M, Lloyd R, Pepin X, Rostami-Hodjegan A, Sjögren E, Tannergren C, Turner DB, Wagner C, Weitschies W, Dressman J. Kostewicz ES, et al. Among authors: galetin a. Eur J Pharm Sci. 2014 Jun 16;57:300-21. doi: 10.1016/j.ejps.2013.09.008. Epub 2013 Sep 21. Eur J Pharm Sci. 2014. PMID: 24060672 Review.

6

The use of ROC analysis for the qualitative prediction of human oral bioavailability from animal data.

Olivares-Morales A, Hatley OJ, Turner D, Galetin A, Aarons L, Rostami-Hodjegan A. Olivares-Morales A, et al. Among authors: galetin a. Pharm Res. 2014 Mar;31(3):720-30. doi: 10.1007/s11095-013-1193-2. Epub 2013 Sep 27. Pharm Res. 2014. PMID: 24072264 Free PMC article.

7

Identification of the effect of multiple polymorphisms on the pharmacokinetics of simvastatin and simvastatin acid using a population-modeling approach.

Tsamandouras N, Dickinson G, Guo Y, Hall S, Rostami-Hodjegan A, Galetin A, Aarons L. Tsamandouras N, et al. Among authors: galetin a. Clin Pharmacol Ther. 2014 Jul;96(1):90-100. doi: 10.1038/clpt.2014.55. Epub 2014 Mar 5. Clin Pharmacol Ther. 2014. PMID: 24598718

8

Quantitative ADME proteomics - CYP and UGT enzymes in the Beagle dog liver and intestine.

Heikkinen AT, Friedlein A, Matondo M, Hatley OJ, Petsalo A, Juvonen R, Galetin A, Rostami-Hodjegan A, Aebersold R, Lamerz J, Dunkley T, Cutler P, Parrott N. Heikkinen AT, et al. Among authors: galetin a. Pharm Res. 2015 Jan;32(1):74-90. doi: 10.1007/s11095-014-1446-8. Epub 2014 Jul 18. Pharm Res. 2015. PMID: 25033762

9

Development and Application of a Mechanistic Pharmacokinetic Model for Simvastatin and its Active Metabolite Simvastatin Acid Using an Integrated Population PBPK Approach.

Tsamandouras N, Dickinson G, Guo Y, Hall S, Rostami-Hodjegan A, Galetin A, Aarons L. Tsamandouras N, et al. Among authors: galetin a. Pharm Res. 2015 Jun;32(6):1864-83. doi: 10.1007/s11095-014-1581-2. Epub 2014 Dec 2. Pharm Res. 2015. PMID: 25446771 Clinical Trial.

10

Meta-analysis of expression of hepatic organic anion-transporting polypeptide (OATP) transporters in cellular systems relative to human liver tissue.

Badée J, Achour B, Rostami-Hodjegan A, Galetin A. Badée J, et al. Among authors: galetin a. Drug Metab Dispos. 2015 Apr;43(4):424-32. doi: 10.1124/dmd.114.062034. Epub 2015 Jan 6. Drug Metab Dispos. 2015. PMID: 25564656

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