Tan SPF - Search Results

1

Facing the Facts of Altered Plasma Protein Binding: Do Current Models Correctly Predict Changes in Fraction Unbound in Special Populations?

Al-Qassabi J, Tan SPF, Phonboon P, Galetin A, Rostami-Hodjegan A, Scotcher D. Al-Qassabi J, et al. Among authors: tan spf. J Pharm Sci. 2024 Jun;113(6):1664-1673. doi: 10.1016/j.xphs.2024.02.024. Epub 2024 Feb 28. J Pharm Sci. 2024. PMID: 38417790 Free article.

2

Effect of Chronic Kidney Disease on the Renal Secretion via Organic Anion Transporters 1/3: Implications for Physiologically-Based Pharmacokinetic Modeling and Dose Adjustment.

Tan SPF, Scotcher D, Rostami-Hodjegan A, Galetin A. Tan SPF, et al. Clin Pharmacol Ther. 2022 Sep;112(3):643-652. doi: 10.1002/cpt.2642. Epub 2022 Jun 13. Clin Pharmacol Ther. 2022. PMID: 35569107 Free PMC article.

3

Development of 4-Pyridoxic Acid PBPK Model to Support Biomarker-Informed Evaluation of OAT1/3 Inhibition and Effect of Chronic Kidney Disease.

Tan SPF, Willemin ME, Snoeys J, Shen H, Rostami-Hodjegan A, Scotcher D, Galetin A. Tan SPF, et al. Clin Pharmacol Ther. 2023 Dec;114(6):1243-1253. doi: 10.1002/cpt.3029. Epub 2023 Sep 8. Clin Pharmacol Ther. 2023. PMID: 37620246

4

Albumin-Mediated Drug Uptake by Organic Anion Transporter 1/3 Is Real: Implications for the Prediction of Active Renal Secretion Clearance.

Tan SPF, Tillmann A, Murby SJ, Rostami-Hodjegan A, Scotcher D, Galetin A. Tan SPF, et al. Mol Pharm. 2024 Sep 2;21(9):4603-4617. doi: 10.1021/acs.molpharmaceut.4c00504. Epub 2024 Aug 21. Mol Pharm. 2024. PMID: 39166754 Free PMC article.

5

Mechanistic Middle-Out Physiologically Based Toxicokinetic Modeling of Transporter-Dependent Disposition of Perfluorooctanoic Acid in Humans.

Lin J, Chin SY, Tan SPF, Koh HC, Cheong EJY, Chan ECY, Chan JCY. Lin J, et al. Among authors: tan spf. Environ Sci Technol. 2023 May 2;57(17):6825-6834. doi: 10.1021/acs.est.2c05642. Epub 2023 Apr 18. Environ Sci Technol. 2023. PMID: 37072124 Free PMC article.

6

Predicting human tissue exposures to xenobiotics using a bottom-up physiologically-based biokinetic model.

Tan SPF, Chan ECY, Chan JCY. Tan SPF, et al. ALTEX. 2021;38(2):253-268. doi: 10.14573/altex.2007151. Epub 2020 Nov 17. ALTEX. 2021. PMID: 33219385 Free article.

7

Physiologically-Based Pharmacokinetic Modeling to Predict the Clinical Efficacy of the Coadministration of Lopinavir and Ritonavir against SARS-CoV-2.

Thakur A, Tan SPF, Chan JCY. Thakur A, et al. Among authors: tan spf. Clin Pharmacol Ther. 2020 Dec;108(6):1176-1184. doi: 10.1002/cpt.2014. Epub 2020 Oct 6. Clin Pharmacol Ther. 2020. PMID: 32767755 Free PMC article.

8

Bottom-up physiologically-based biokinetic modelling as an alternative to animal testing.

Chan JCY, Tan SPF, Upton Z, Chan ECY. Chan JCY, et al. Among authors: tan spf. ALTEX. 2019;36(4):597-612. doi: 10.14573/altex.1812051. Epub 2019 May 10. ALTEX. 2019. PMID: 31079160 Free article.

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