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Ebola virus VP35 interacts non-covalently with ubiquitin chains to promote viral replication.
Rodríguez-Salazar CA, van Tol S, Mailhot O, Gonzalez-Orozco M, Galdino GT, Warren AN, Teruel N, Behera P, Afreen KS, Zhang L, Juelich TL, Smith JK, Zylber MI, Freiberg AN, Najmanovich RJ, Giraldo MI, Rajsbaum R. Rodríguez-Salazar CA, et al. Among authors: van tol s. PLoS Biol. 2024 Feb 29;22(2):e3002544. doi: 10.1371/journal.pbio.3002544. eCollection 2024 Feb. PLoS Biol. 2024. PMID: 38422166 Free PMC article.
The TRIMendous Role of TRIMs in Virus-Host Interactions.
van Tol S, Hage A, Giraldo MI, Bharaj P, Rajsbaum R. van Tol S, et al. Vaccines (Basel). 2017 Aug 22;5(3):23. doi: 10.3390/vaccines5030023. Vaccines (Basel). 2017. PMID: 28829373 Free PMC article. Review.
Envelope protein ubiquitination drives entry and pathogenesis of Zika virus.
Giraldo MI, Xia H, Aguilera-Aguirre L, Hage A, van Tol S, Shan C, Xie X, Sturdevant GL, Robertson SJ, McNally KL, Meade-White K, Azar SR, Rossi SL, Maury W, Woodson M, Ramage H, Johnson JR, Krogan NJ, Morais MC, Best SM, Shi PY, Rajsbaum R. Giraldo MI, et al. Among authors: van tol s. Nature. 2020 Sep;585(7825):414-419. doi: 10.1038/s41586-020-2457-8. Epub 2020 Jul 8. Nature. 2020. PMID: 32641828 Free PMC article.
TRIM Proteins in Host Defense and Viral Pathogenesis.
Giraldo MI, Hage A, van Tol S, Rajsbaum R. Giraldo MI, et al. Among authors: van tol s. Curr Clin Microbiol Rep. 2020;7(4):101-114. doi: 10.1007/s40588-020-00150-8. Epub 2020 Aug 8. Curr Clin Microbiol Rep. 2020. PMID: 32837832 Free PMC article. Review.
SARS-CoV-2 proteases PLpro and 3CLpro cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species.
Moustaqil M, Ollivier E, Chiu HP, Van Tol S, Rudolffi-Soto P, Stevens C, Bhumkar A, Hunter DJB, Freiberg AN, Jacques D, Lee B, Sierecki E, Gambin Y. Moustaqil M, et al. Among authors: van tol s. Emerg Microbes Infect. 2021 Dec;10(1):178-195. doi: 10.1080/22221751.2020.1870414. Emerg Microbes Infect. 2021. PMID: 33372854 Free PMC article.
The RNA helicase DHX16 recognizes specific viral RNA to trigger RIG-I-dependent innate antiviral immunity.
Hage A, Bharaj P, van Tol S, Giraldo MI, Gonzalez-Orozco M, Valerdi KM, Warren AN, Aguilera-Aguirre L, Xie X, Widen SG, Moulton HM, Lee B, Johnson JR, Krogan NJ, García-Sastre A, Shi PY, Freiberg AN, Rajsbaum R. Hage A, et al. Among authors: van tol s. Cell Rep. 2022 Mar 8;38(10):110434. doi: 10.1016/j.celrep.2022.110434. Cell Rep. 2022. PMID: 35263596 Free PMC article.
Ubiquitination of Ebola virus VP35 at lysine 309 regulates viral transcription and assembly.
van Tol S, Kalveram B, Ilinykh PA, Ronk A, Huang K, Aguilera-Aguirre L, Bharaj P, Hage A, Atkins C, Giraldo MI, Wakamiya M, Gonzalez-Orozco M, Warren AN, Bukreyev A, Freiberg AN, Rajsbaum R. van Tol S, et al. PLoS Pathog. 2022 May 9;18(5):e1010532. doi: 10.1371/journal.ppat.1010532. eCollection 2022 May. PLoS Pathog. 2022. PMID: 35533195 Free PMC article.
32 results