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High-throughput virtual search of small molecules for controlling the mechanical stability of human CD4.
Reifs A, Fernandez-Calvo A, Alonso-Lerma B, Schönfelder J, Franco D, Ortega-Muñoz M, Casares S, Jimenez-Lopez C, Saa L, Cortajarena AL, De Sancho D, San Sebastian E, Perez-Jimenez R. Reifs A, et al. Among authors: saa l. J Biol Chem. 2024 Apr;300(4):107133. doi: 10.1016/j.jbc.2024.107133. Epub 2024 Mar 2. J Biol Chem. 2024. PMID: 38432632 Free PMC article.
The strongest protein binder is surprisingly labile.
Fernandez-Calvo A, Reifs A, Saa L, Cortajarena AL, De Sancho D, Perez-Jimenez R. Fernandez-Calvo A, et al. Among authors: saa l. Protein Sci. 2024 Jul;33(7):e5030. doi: 10.1002/pro.5030. Protein Sci. 2024. PMID: 38864696 Free PMC article.
45 results