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Lipid nanoparticle structure and delivery route during pregnancy dictate mRNA potency, immunogenicity, and maternal and fetal outcomes.
Proc Natl Acad Sci U S A. 2024 Mar 12;121(11):e2307810121. doi: 10.1073/pnas.2307810121. Epub 2024 Mar 4.
Proc Natl Acad Sci U S A. 2024.
PMID: 38437545
Free PMC article.
Branched-Tail Lipid Nanoparticles for Intravenous mRNA Delivery to Lung Immune, Endothelial, and Alveolar Cells in Mice.
Petersen DMS, Weiss RM, Hajj KA, Yerneni SS, Chaudhary N, Newby AN, Arral ML, Whitehead KA.
Petersen DMS, et al.
Adv Healthc Mater. 2024 Sep;13(22):e2400225. doi: 10.1002/adhm.202400225. Epub 2024 Jul 2.
Adv Healthc Mater. 2024.
PMID: 38888972
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