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Page 1
Guiding the HBO1 complex function through the JADE subunit.
Gaurav N, Kanai A, Lachance C, Cox KL, Liu J, Grzybowski AT, Saksouk N, Klein BJ, Komata Y, Asada S, Ruthenburg AJ, Poirier MG, Côté J, Yokoyama A, Kutateladze TG. Gaurav N, et al. Among authors: cox kl. Nat Struct Mol Biol. 2024 Jul;31(7):1039-1049. doi: 10.1038/s41594-024-01245-2. Epub 2024 Mar 6. Nat Struct Mol Biol. 2024. PMID: 38448574
Covalent Modifications of Histone H3K9 Promote Binding of CHD3.
Tencer AH, Cox KL, Di L, Bridgers JB, Lyu J, Wang X, Sims JK, Weaver TM, Allen HF, Zhang Y, Gatchalian J, Darcy MA, Gibson MD, Ikebe J, Li W, Wade PA, Hayes JJ, Strahl BD, Kono H, Poirier MG, Musselman CA, Kutateladze TG. Tencer AH, et al. Among authors: cox kl. Cell Rep. 2017 Oct 10;21(2):455-466. doi: 10.1016/j.celrep.2017.09.054. Cell Rep. 2017. PMID: 29020631 Free PMC article.
Accessibility of the histone H3 tail in the nucleosome for binding of paired readers.
Gatchalian J, Wang X, Ikebe J, Cox KL, Tencer AH, Zhang Y, Burge NL, Di L, Gibson MD, Musselman CA, Poirier MG, Kono H, Hayes JJ, Kutateladze TG. Gatchalian J, et al. Among authors: cox kl. Nat Commun. 2017 Nov 14;8(1):1489. doi: 10.1038/s41467-017-01598-x. Nat Commun. 2017. PMID: 29138400 Free PMC article.
Mechanism for autoinhibition and activation of the MORC3 ATPase.
Zhang Y, Klein BJ, Cox KL, Bertulat B, Tencer AH, Holden MR, Wright GM, Black J, Cardoso MC, Poirier MG, Kutateladze TG. Zhang Y, et al. Among authors: cox kl. Proc Natl Acad Sci U S A. 2019 Mar 26;116(13):6111-6119. doi: 10.1073/pnas.1819524116. Epub 2019 Mar 8. Proc Natl Acad Sci U S A. 2019. PMID: 30850548 Free PMC article.
Molecular mechanism of the MORC4 ATPase activation.
Tencer AH, Cox KL, Wright GM, Zhang Y, Petell CJ, Klein BJ, Strahl BD, Black JC, Poirier MG, Kutateladze TG. Tencer AH, et al. Among authors: cox kl. Nat Commun. 2020 Oct 29;11(1):5466. doi: 10.1038/s41467-020-19278-8. Nat Commun. 2020. PMID: 33122719 Free PMC article.
The role of the PZP domain of AF10 in acute leukemia driven by AF10 translocations.
Klein BJ, Deshpande A, Cox KL, Xuan F, Zandian M, Barbosa K, Khanal S, Tong Q, Zhang Y, Zhang P, Sinha A, Bohlander SK, Shi X, Wen H, Poirier MG, Deshpande AJ, Kutateladze TG. Klein BJ, et al. Among authors: cox kl. Nat Commun. 2021 Jul 5;12(1):4130. doi: 10.1038/s41467-021-24418-9. Nat Commun. 2021. PMID: 34226546 Free PMC article.
HIV-1 Preintegration Complex Preferentially Integrates the Viral DNA into Nucleosomes Containing Trimethylated Histone 3-Lysine 36 Modification and Flanking Linker DNA.
Sapp N, Burge N, Cox K, Prakash P, Balasubramaniam M, Thapa S, Christensen D, Li M, Linderberger J, Kvaratskhelia M, Pandhare J, Craigie R, Poirier MG, Dash C. Sapp N, et al. J Virol. 2022 Sep 28;96(18):e0101122. doi: 10.1128/jvi.01011-22. Epub 2022 Sep 12. J Virol. 2022. PMID: 36094316 Free PMC article.
MORF and MOZ acetyltransferases target unmethylated CpG islands through the winged helix domain.
Becht DC, Klein BJ, Kanai A, Jang SM, Cox KL, Zhou BR, Phanor SK, Zhang Y, Chen RW, Ebmeier CC, Lachance C, Galloy M, Fradet-Turcotte A, Bulyk ML, Bai Y, Poirier MG, Côté J, Yokoyama A, Kutateladze TG. Becht DC, et al. Among authors: cox kl. Nat Commun. 2023 Feb 8;14(1):697. doi: 10.1038/s41467-023-36368-5. Nat Commun. 2023. PMID: 36754959 Free PMC article.
280 results