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Page 1
Functional Characterization of Cooperating MGA Mutations in RUNX1::RUNX1T1 Acute Myeloid Leukemia.
Klco J, Thomas M 3rd, Qi W, Walsh M, Ma J, Westover T, Abdelhamed S, Ezzell L, Rolle C, Xiong E, Rosikiewicz W, Xu B, Pruett-Miller S, Loughran A, Janke L. Klco J, et al. Among authors: westover t. Res Sq [Preprint]. 2023 Sep 22:rs.3.rs-3315059. doi: 10.21203/rs.3.rs-3315059/v1. Res Sq. 2023. Update in: Leukemia. 2024 May;38(5):991-1002. doi: 10.1038/s41375-024-02193-y. PMID: 37790524 Free PMC article. Updated. Preprint.
Mutant Samd9l expression impairs hematopoiesis and induces bone marrow failure in mice.
Abdelhamed S, Thomas ME 3rd, Westover T, Umeda M, Xiong E, Rolle C, Walsh MP, Wu H, Schwartz JR, Valentine V, Valentine M, Pounds S, Ma J, Janke LJ, Klco JM. Abdelhamed S, et al. Among authors: westover t. J Clin Invest. 2022 Nov 1;132(21):e158869. doi: 10.1172/JCI158869. J Clin Invest. 2022. PMID: 36074606 Free PMC article.
Acute myeloid leukemias with UBTF tandem duplications are sensitive to menin inhibitors.
Barajas JM, Rasouli M, Umeda M, Hiltenbrand R, Abdelhamed S, Mohnani R, Arthur B, Westover T, Thomas ME 3rd, Ashtiani M, Janke LJ, Xu B, Chang TC, Rosikiewicz W, Xiong E, Rolle C, Low J, Krishan R, Song G, Walsh MP, Ma J, Rubnitz JE, Iacobucci I, Chen T, Krippner-Heidenreich A, Zwaan CM, Heidenreich O, Klco JM. Barajas JM, et al. Among authors: westover t. Blood. 2024 Feb 15;143(7):619-630. doi: 10.1182/blood.2023021359. Blood. 2024. PMID: 37890156 Free PMC article.
UBTF Tandem Duplications in Pediatric MDS and AML: Implications for Clinical Screening and Diagnosis.
Barajas JM, Umeda M, Contreras L, Khanlari M, Westover T, Walsh MP, Xiong E, Yang C, Otero B, Arribas-Layton M, Abdelhamed S, Song G, Ma X, Thomas ME, Ma J, Klco JM. Barajas JM, et al. Among authors: westover t. medRxiv [Preprint]. 2023 Nov 13:2023.11.13.23298320. doi: 10.1101/2023.11.13.23298320. medRxiv. 2023. Update in: Haematologica. 2024 Aug 01;109(8):2459-2468. doi: 10.3324/haematol.2023.284683. PMID: 38014207 Free PMC article. Updated. Preprint.
UBTF tandem duplications in pediatric myelodysplastic syndrome and acute myeloid leukemia: implications for clinical screening and diagnosis.
Barajas JM, Umeda M, Contreras L, Khanlari M, Westover T, Walsh MP, Xiong E, Yang C, Otero B, Arribas-Layton M, Abdelhamed S, Song G, Ma X, Thomas Rd ME, Ma J, Klco JM. Barajas JM, et al. Among authors: westover t. Haematologica. 2024 Aug 1;109(8):2459-2468. doi: 10.3324/haematol.2023.284683. Haematologica. 2024. PMID: 38426285 Free PMC article.
Integrated Genomic Analysis Identifies UBTF Tandem Duplications as a Recurrent Lesion in Pediatric Acute Myeloid Leukemia.
Umeda M, Ma J, Huang BJ, Hagiwara K, Westover T, Abdelhamed S, Barajas JM, Thomas ME, Walsh MP, Song G, Tian L, Liu Y, Chen X, Kolekar P, Tran Q, Foy SG, Maciaszek JL, Kleist AB, Leonti AR, Ju B, Easton J, Wu H, Valentine V, Valentine MB, Liu YC, Ries RE, Smith JL, Parganas E, Iacobucci I, Hiltenbrand R, Miller J, Myers JR, Rampersaud E, Rahbarinia D, Rusch M, Wu G, Inaba H, Wang YC, Alonzo TA, Downing JR, Mullighan CG, Pounds S, Babu MM, Zhang J, Rubnitz JE, Meshinchi S, Ma X, Klco JM. Umeda M, et al. Among authors: westover t. Blood Cancer Discov. 2022 May 5;3(3):194-207. doi: 10.1158/2643-3230.BCD-21-0160. Blood Cancer Discov. 2022. PMID: 35176137 Free PMC article.
Proposal of a new genomic framework for categorization of pediatric acute myeloid leukemia associated with prognosis.
Umeda M, Ma J, Westover T, Ni Y, Song G, Maciaszek JL, Rusch M, Rahbarinia D, Foy S, Huang BJ, Walsh MP, Kumar P, Liu Y, Fan Y, Wu G, Baker SD, Ma X, Wang L, Rubnitz JE, Pounds S, Klco JM. Umeda M, et al. Among authors: westover t. Res Sq [Preprint]. 2023 May 29:rs.3.rs-2925426. doi: 10.21203/rs.3.rs-2925426/v1. Res Sq. 2023. Update in: Nat Genet. 2024 Feb;56(2):281-293. doi: 10.1038/s41588-023-01640-3. PMID: 37398194 Free PMC article. Updated. Preprint.
A new genomic framework to categorize pediatric acute myeloid leukemia.
Umeda M, Ma J, Westover T, Ni Y, Song G, Maciaszek JL, Rusch M, Rahbarinia D, Foy S, Huang BJ, Walsh MP, Kumar P, Liu Y, Yang W, Fan Y, Wu G, Baker SD, Ma X, Wang L, Alonzo TA, Rubnitz JE, Pounds S, Klco JM. Umeda M, et al. Among authors: westover t. Nat Genet. 2024 Feb;56(2):281-293. doi: 10.1038/s41588-023-01640-3. Epub 2024 Jan 11. Nat Genet. 2024. PMID: 38212634 Free PMC article.
45 results