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The nutrient-sensing Rag-GTPase complex in B cells controls humoral immunity via TFEB/TFE3-dependent mitochondrial fitness.
Zhu X, Wu Y, Li Y, Zhou X, Watzlawik JO, Chen YM, Raybuck AL, Billadeau D, Shapiro V, Springer W, Sun J, Boothby MR, Zeng H. Zhu X, et al. Among authors: shapiro v. bioRxiv [Preprint]. 2024 Mar 12:2024.02.26.582122. doi: 10.1101/2024.02.26.582122. bioRxiv. 2024. Update in: Nat Commun. 2024 Nov 23;15(1):10163. doi: 10.1038/s41467-024-54344-5 PMID: 38463988 Free PMC article. Updated. Preprint.
Transcription factor Tox2 is required for metabolic adaptation and tissue residency of ILC3 in the gut.
Das A, Martinez-Ruiz GU, Bouladoux N, Stacy A, Moraly J, Vega-Sendino M, Zhao Y, Lavaert M, Ding Y, Morales-Sanchez A, Harly C, Seedhom MO, Chari R, Awasthi P, Ikeuchi T, Wang Y, Zhu J, Moutsopoulos NM, Chen W, Yewdell JW, Shapiro VS, Ruiz S, Taylor N, Belkaid Y, Bhandoola A. Das A, et al. Among authors: shapiro vs. Immunity. 2024 May 14;57(5):1019-1036.e9. doi: 10.1016/j.immuni.2024.04.001. Epub 2024 Apr 26. Immunity. 2024. PMID: 38677292
Rag-GTPase-TFEB/TFE3 axis controls B cell mitochondrial fitness and humoral immunity independent of mTORC1.
Zhu X, Wu Y, Li Y, Zhou X, Watzlawik JO, Chen YM, Raybuck AL, Billadeau D, Shapiro V, Springer W, Sun J, Boothby MR, Zeng H. Zhu X, et al. Among authors: shapiro v. Res Sq [Preprint]. 2024 Mar 29:rs.3.rs-3957355. doi: 10.21203/rs.3.rs-3957355/v1. Res Sq. 2024. Update in: Nat Commun. 2024 Nov 23;15(1):10163. doi: 10.1038/s41467-024-54344-5 PMID: 38585731 Free PMC article. Updated. Preprint.
Cutting Edge: Enhanced Antitumor Immunity in ST8Sia6 Knockout Mice.
Friedman DJ, Kizerwetter M, Belmonte P, Rajcula M, Theodore K, Kim Lee HS, Shapiro MJ, Dong H, Shapiro VS. Friedman DJ, et al. Among authors: shapiro vs. J Immunol. 2022 Apr 15;208(8):1845-1850. doi: 10.4049/jimmunol.2101165. Epub 2022 Apr 4. J Immunol. 2022. PMID: 35379746 Free PMC article.
139 results