Cuthbertson P - Search Results

1

Graft-versus-leukaemia immunity is retained following treatment with post-transplant cyclophosphamide alone or combined with tocilizumab in humanised mice.

Sligar C, Reilly E, Cuthbertson P, Vine KL, Bird KM, Elhage A, Alexander SI, Sluyter R, Watson D. Sligar C, et al. Among authors: cuthbertson p. Clin Transl Immunology. 2024 Mar 15;13(3):e1497. doi: 10.1002/cti2.1497. eCollection 2024. Clin Transl Immunology. 2024. PMID: 38495918 Free PMC article.

2

Post-transplant cyclophosphamide limits reactive donor T cells and delays the development of graft-versus-host disease in a humanized mouse model.

Adhikary SR, Cuthbertson P, Nicholson L, Bird KM, Sligar C, Hu M, O'Connell PJ, Sluyter R, Alexander SI, Watson D. Adhikary SR, et al. Among authors: cuthbertson p. Immunology. 2021 Oct;164(2):332-347. doi: 10.1111/imm.13374. Epub 2021 Jun 13. Immunology. 2021. PMID: 34021907 Free PMC article.

3

Insights into mechanisms of graft-versus-host disease through humanised mouse models.

Elhage A, Sligar C, Cuthbertson P, Watson D, Sluyter R. Elhage A, et al. Among authors: cuthbertson p. Biosci Rep. 2022 Sep 30;42(9):BSR20211986. doi: 10.1042/BSR20211986. Biosci Rep. 2022. PMID: 35993192 Free PMC article. Review.

4

Tocilizumab increases regulatory T cells, reduces natural killer cells and delays graft-versus-host disease development in humanized mice treated with post-transplant cyclophosphamide.

Sligar C, Cuthbertson P, Miles NA, Adhikary SR, Elhage A, Zhang G, Alexander SI, Sluyter R, Watson D. Sligar C, et al. Among authors: cuthbertson p. Immunol Cell Biol. 2023 Aug;101(7):639-656. doi: 10.1111/imcb.12652. Epub 2023 May 16. Immunol Cell Biol. 2023. PMID: 37191045

5

A Species-Specific Anti-Human P2X7 Monoclonal Antibody Reduces Graft-versus-Host Disease in Humanised Mice.

Elhage A, Cuthbertson P, Sligar C, Watson D, Sluyter R. Elhage A, et al. Among authors: cuthbertson p. Pharmaceutics. 2023 Aug 31;15(9):2263. doi: 10.3390/pharmaceutics15092263. Pharmaceutics. 2023. PMID: 37765233 Free PMC article.

6

Post-Transplant Cyclophosphamide Combined with Brilliant Blue G Reduces Graft-versus-Host Disease without Compromising Graft-versus-Leukaemia Immunity in Humanised Mice.

Cuthbertson P, Button A, Sligar C, Elhage A, Vine KL, Watson D, Sluyter R. Cuthbertson P, et al. Int J Mol Sci. 2024 Feb 1;25(3):1775. doi: 10.3390/ijms25031775. Int J Mol Sci. 2024. PMID: 38339054 Free PMC article.

7

Altered donor P2X7 activity in human leukocytes correlates with P2RX7 genotype but does not affect the development of graft-versus-host disease in humanised mice.

Adhikary SR, Geraghty NJ, Cuthbertson P, Sluyter R, Watson D. Adhikary SR, et al. Among authors: cuthbertson p. Purinergic Signal. 2019 Jun;15(2):177-192. doi: 10.1007/s11302-019-09651-8. Epub 2019 Apr 18. Purinergic Signal. 2019. PMID: 31001750 Free PMC article.

8

Increased P2X7 expression in the gastrointestinal tract and skin in a humanised mouse model of graft-versus-host disease.

Cuthbertson P, Adhikary SR, Geraghty NJ, Guy TV, Hadjiashrafi A, Fuller SJ, Ly D, Watson D, Sluyter R. Cuthbertson P, et al. Clin Sci (Lond). 2020 Jan 31;134(2):207-223. doi: 10.1042/CS20191086. Clin Sci (Lond). 2020. PMID: 31934722

9

A single-nucleotide polymorphism in the human ENTPD1 gene encoding CD39 is associated with worsened graft-versus-host disease in a humanized mouse model.

Adhikary SR, Cuthbertson P, Turner RJ, Sluyter R, Watson D. Adhikary SR, et al. Among authors: cuthbertson p. Immunol Cell Biol. 2020 May;98(5):397-410. doi: 10.1111/imcb.12328. Epub 2020 Apr 16. Immunol Cell Biol. 2020. PMID: 32181525

10

P2X7 receptor antagonism increases regulatory T cells and reduces clinical and histological graft-versus-host disease in a humanised mouse model.

Cuthbertson P, Geraghty NJ, Adhikary SR, Casolin S, Watson D, Sluyter R. Cuthbertson P, et al. Clin Sci (Lond). 2021 Feb 12;135(3):495-513. doi: 10.1042/CS20201352. Clin Sci (Lond). 2021. PMID: 33463682

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