Luo P - Search Results

1

STEP: profiling cellular-specific targets and pathways of bioactive small molecules in tissues via integrating single-cell transcriptomics and chemoproteomics.

Chen J, Chu Z, Zhang Q, Wang C, Luo P, Zhang Y, Xia F, Gu L, Wong YK, Shi Q, Xu C, Tang H, Wang J. Chen J, et al. Among authors: luo p. Chem Sci. 2024 Mar 5;15(12):4313-4321. doi: 10.1039/d3sc04826h. eCollection 2024 Mar 20. Chem Sci. 2024. PMID: 38516082 Free PMC article.

2

Dihydroartemisinin Inhibits the Proliferation of Leukemia Cells K562 by Suppressing PKM2 and GLUT1 Mediated Aerobic Glycolysis.

Gao P, Shen S, Li X, Liu D, Meng Y, Liu Y, Zhu Y, Zhang J, Luo P, Gu L. Gao P, et al. Among authors: luo p. Drug Des Devel Ther. 2020 May 27;14:2091-2100. doi: 10.2147/DDDT.S248872. eCollection 2020. Drug Des Devel Ther. 2020. PMID: 32546972 Free PMC article.

3

Celastrol exerts a neuroprotective effect by directly binding to HMGB1 protein in cerebral ischemia-reperfusion.

Liu DD, Luo P, Gu L, Zhang Q, Gao P, Zhu Y, Chen X, Guo Q, Zhang J, Ma N, Wang J. Liu DD, et al. Among authors: luo p. J Neuroinflammation. 2021 Aug 9;18(1):174. doi: 10.1186/s12974-021-02216-w. J Neuroinflammation. 2021. PMID: 34372857 Free PMC article.

4

Transcriptome and Lipid Metabolomics-Based Discovery: Glycyrrhizic Acid Alleviates Tripterygium Glycoside Tablet-Induced Acute Liver Injury by Regulating the Activities of CYP and the Metabolism of Phosphoglycerides.

Shi Q, Wang Q, Chen J, Xia F, Qiu C, Li M, Zhao M, Zhang Q, Luo P, Lu T, Zhang Y, Xu L, He X, Zhong T, Lin N, Guo Q. Shi Q, et al. Among authors: luo p. Front Pharmacol. 2022 Feb 14;12:822154. doi: 10.3389/fphar.2021.822154. eCollection 2021. Front Pharmacol. 2022. PMID: 35237151 Free PMC article.

5

Dissection of Targeting Molecular Mechanisms of Aristolochic Acid-induced Nephrotoxicity via a Combined Deconvolution Strategy of Chemoproteomics and Metabolomics.

Zhang Q, Luo P, Chen J, Yang C, Xia F, Zhang J, Tang H, Liu D, Gu L, Shi Q, He X, Yang T, Wang J. Zhang Q, et al. Among authors: luo p. Int J Biol Sci. 2022 Feb 21;18(5):2003-2017. doi: 10.7150/ijbs.69618. eCollection 2022. Int J Biol Sci. 2022. PMID: 35342337 Free PMC article.

6

Celastrol mitigates inflammation in sepsis by inhibiting the PKM2-dependent Warburg effect.

Luo P, Zhang Q, Zhong TY, Chen JY, Zhang JZ, Tian Y, Zheng LH, Yang F, Dai LY, Zou C, Li ZJ, Liu JH, Wang JG. Luo P, et al. Mil Med Res. 2022 May 20;9(1):22. doi: 10.1186/s40779-022-00381-4. Mil Med Res. 2022. PMID: 35596191 Free PMC article.

7

Celastrol induces ferroptosis in activated HSCs to ameliorate hepatic fibrosis via targeting peroxiredoxins and HO-1.

Luo P, Liu D, Zhang Q, Yang F, Wong YK, Xia F, Zhang J, Chen J, Tian Y, Yang C, Dai L, Shen HM, Wang J. Luo P, et al. Acta Pharm Sin B. 2022 May;12(5):2300-2314. doi: 10.1016/j.apsb.2021.12.007. Epub 2021 Dec 18. Acta Pharm Sin B. 2022. PMID: 35646542 Free PMC article.

8

Neuroprotective Effects of Celastrol in Neurodegenerative Diseases-Unscramble Its Major Mechanisms of Action and Targets.

Liu D, Zhang Q, Luo P, Gu L, Shen S, Tang H, Zhang Y, Lyu M, Shi Q, Yang C, Wang J. Liu D, et al. Among authors: luo p. Aging Dis. 2022 Jun 1;13(3):815-836. doi: 10.14336/AD.2021.1115. eCollection 2022 Jun. Aging Dis. 2022. PMID: 35656110 Free PMC article. Review.

9

Integrated single-cell transcriptomics and proteomics reveal cellular-specific responses and microenvironment remodeling in aristolochic acid nephropathy.

Chen J, Luo P, Wang C, Yang C, Bai Y, He X, Zhang Q, Zhang J, Yang J, Wang S, Wang J. Chen J, et al. Among authors: luo p. JCI Insight. 2022 Aug 22;7(16):e157360. doi: 10.1172/jci.insight.157360. JCI Insight. 2022. PMID: 35852860 Free PMC article.

10

Capsaicin ameliorates inflammation in a TRPV1-independent mechanism by inhibiting PKM2-LDHA-mediated Warburg effect in sepsis.

Zhang Q, Luo P, Xia F, Tang H, Chen J, Zhang J, Liu D, Zhu Y, Liu Y, Gu L, Zheng L, Li Z, Yang F, Dai L, Liao F, Xu C, Wang J. Zhang Q, et al. Among authors: luo p. Cell Chem Biol. 2022 Aug 18;29(8):1248-1259.e6. doi: 10.1016/j.chembiol.2022.06.011. Epub 2022 Jul 19. Cell Chem Biol. 2022. PMID: 35858615 Free article.

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