Alsfouk AA - Search Results

1

Integrated study of Quercetin as a potent SARS-CoV-2 RdRp inhibitor: Binding interactions, MD simulations, and In vitro assays.

Metwaly AM, El-Fakharany EM, Alsfouk AA, Ibrahim IM, Elkaeed EB, Eissa IH. Metwaly AM, et al. Among authors: alsfouk aa. PLoS One. 2024 Dec 3;19(12):e0312866. doi: 10.1371/journal.pone.0312866. eCollection 2024. PLoS One. 2024. PMID: 39625895

2

New N-amino-5-cyano-6-pyridones as antimicrobial small molecules endowed with DNA gyrase a inhibitory activity: design, one-pot synthesis, biological assessment and in silico insights.

Kamaly OA, Younes AS, Harras MF, Sabour R, Alsfouk AA, Ibrahim MH. Kamaly OA, et al. Among authors: alsfouk aa. BMC Chem. 2024 Nov 13;18(1):226. doi: 10.1186/s13065-024-01342-9. BMC Chem. 2024. PMID: 39538322 Free PMC article.

3

Development of novel CDK9 and CYP3A4 inhibitors for cancer therapy through field and computational approaches.

Alsfouk AA, Faris A, Cacciatore I, Alnajjar R. Alsfouk AA, et al. Front Chem. 2024 Oct 21;12:1473398. doi: 10.3389/fchem.2024.1473398. eCollection 2024. Front Chem. 2024. PMID: 39498375 Free PMC article.

4

Anti-proliferative 2,3-dihydro-1,3,4-thiadiazoles targeting VEGFR-2: Design, synthesis, in vitro, and in silico studies.

Elkady H, Elgammal WE, Mahdy HA, Zara S, Carradori S, Husein DZ, Alsfouk AA, Ibrahim IM, Elkaeed EB, Metwaly AM, Eissa IH. Elkady H, et al. Among authors: alsfouk aa. Comput Biol Chem. 2024 Sep 23;113:108221. doi: 10.1016/j.compbiolchem.2024.108221. Online ahead of print. Comput Biol Chem. 2024. PMID: 39332241

5

One-pot synthesis and pharmacological evaluation of new quinoline/pyrimido-diazepines as pulmonary antifibrotic agents.

Fawzy MA, Ibrahim KH, Aly AA, Mohamed AH, Naguib Abdel Hafez SM, Abdelzaher WY, Elkaeed EB, Alsfouk AA, Abdelhafez EM. Fawzy MA, et al. Among authors: alsfouk aa. Future Med Chem. 2024;16(21):2211-2230. doi: 10.1080/17568919.2024.2394018. Epub 2024 Sep 18. Future Med Chem. 2024. PMID: 39291539

6

Discovery and Anticancer Screening of Novel Oxindole-Based Derivative Bearing Pyridyl Group as Potent and Selective Dual FLT3/CDK2 Kinase Inhibitor.

Soudi A, Bender O, Celik I, El-Hafeez AAA, Dogan R, Atalay A, Elkaeed EB, Alsfouk AA, Abdelhafez EMN, Aly OM, Sippl W, Ali TFS. Soudi A, et al. Among authors: alsfouk aa. Pharmaceuticals (Basel). 2024 May 20;17(5):659. doi: 10.3390/ph17050659. Pharmaceuticals (Basel). 2024. PMID: 38794229 Free PMC article.

7

New Theobromine Apoptotic Analogue with Anticancer Potential Targeting the EGFR Protein: Computational and In Vitro Studies.

Eissa IH, Yousef RG, Elkaeed EB, Alsfouk AA, Husein DZ, Ibrahim IM, Ismail A, Elkady H, Metwaly AM. Eissa IH, et al. Among authors: alsfouk aa. ACS Omega. 2024 Mar 27;9(14):15861-15881. doi: 10.1021/acsomega.3c08148. eCollection 2024 Apr 9. ACS Omega. 2024. PMID: 38617602 Free PMC article.

8

New thiazolidine-2,4-diones as potential anticancer agents and apoptotic inducers targeting VEGFR-2 kinase: Design, synthesis, in silico and in vitro studies.

Elkady H, Mahdy HA, Taghour MS, Dahab MA, Elwan A, Hagras M, Hussein MH, Ibrahim IM, Husein DZ, Elkaeed EB, Alsfouk AA, Metwaly AM, Eissa IH. Elkady H, et al. Among authors: alsfouk aa. Biochim Biophys Acta Gen Subj. 2024 Jun;1868(6):130599. doi: 10.1016/j.bbagen.2024.130599. Epub 2024 Mar 21. Biochim Biophys Acta Gen Subj. 2024. PMID: 38521471

9

Rationale design and synthesis of new apoptotic thiadiazole derivatives targeting VEGFR-2: computational and in vitro studies.

Elgammal WE, Elkady H, Mahdy HA, Husein DZ, Alsfouk AA, Alsfouk BA, Ibrahim IM, Elkaeed EB, Metwaly AM, Eissa IH. Elgammal WE, et al. Among authors: alsfouk aa. RSC Adv. 2023 Dec 19;13(51):35853-35876. doi: 10.1039/d3ra07562a. eCollection 2023 Dec 8. RSC Adv. 2023. PMID: 38116168 Free PMC article.

10

Computer-Assisted Drug Discovery of a Novel Theobromine Derivative as an EGFR Protein-Targeted Apoptosis Inducer.

Eissa IH, Yousef RG, Elkaeed EB, Alsfouk AA, Husein DZ, Ibrahim IM, El-Mahdy HA, Elkady H, Metwaly AM. Eissa IH, et al. Among authors: alsfouk aa. Evol Bioinform Online. 2023 Dec 1;19:11769343231217916. doi: 10.1177/11769343231217916. eCollection 2023. Evol Bioinform Online. 2023. PMID: 38046652 Free PMC article.

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