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New thiazolidine-2,4-diones as potential anticancer agents and apoptotic inducers targeting VEGFR-2 kinase: Design, synthesis, in silico and in vitro studies.
Elkady H, Mahdy HA, Taghour MS, Dahab MA, Elwan A, Hagras M, Hussein MH, Ibrahim IM, Husein DZ, Elkaeed EB, Alsfouk AA, Metwaly AM, Eissa IH. Elkady H, et al. Among authors: hagras m. Biochim Biophys Acta Gen Subj. 2024 Jun;1868(6):130599. doi: 10.1016/j.bbagen.2024.130599. Epub 2024 Mar 21. Biochim Biophys Acta Gen Subj. 2024. PMID: 38521471
Synthesis, biological evaluation, and in silico studies of new CDK2 inhibitors based on pyrazolo[3,4-d]pyrimidine and pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine scaffold with apoptotic activity.
Mandour AA, Nassar IF, Abdel Aal MT, Shahin MAE, El-Sayed WA, Hegazy M, Yehia AM, Ismail A, Hagras M, Elkaeed EB, Refaat HM, Ismail NSM. Mandour AA, et al. Among authors: hagras m. J Enzyme Inhib Med Chem. 2022 Dec;37(1):1957-1973. doi: 10.1080/14756366.2022.2086866. J Enzyme Inhib Med Chem. 2022. PMID: 35815597 Free PMC article.
Design, synthesis, and anti-cancer evaluation of new pyrido[2,3-d]pyrimidin-4(3H)-one derivatives as potential EGFRWT and EGFRT790M inhibitors and apoptosis inducers.
Elzahabi HSA, Nossier ES, Alasfoury RA, El-Manawaty M, Sayed SM, Elkaeed EB, Metwaly AM, Hagras M, Eissa IH. Elzahabi HSA, et al. Among authors: hagras m. J Enzyme Inhib Med Chem. 2022 Dec;37(1):1053-1076. doi: 10.1080/14756366.2022.2062752. J Enzyme Inhib Med Chem. 2022. PMID: 35821615 Free PMC article.
Discovery of New Uracil and Thiouracil Derivatives as Potential HDAC Inhibitors.
Elbatrawy OR, Hagras M, El Deeb MA, Agili F, Hegazy M, El-Husseiny AA, Mokhtar MM, Elkhawaga SY, Eissa IH, El-Kalyoubi S. Elbatrawy OR, et al. Among authors: hagras m. Pharmaceuticals (Basel). 2023 Jul 6;16(7):966. doi: 10.3390/ph16070966. Pharmaceuticals (Basel). 2023. PMID: 37513878 Free PMC article.
Design, synthesis, anti-proliferative evaluation, docking, and MD simulation studies of new thieno[2,3-d]pyrimidines targeting VEGFR-2.
El-Metwally SA, Elkady H, Hagras M, Husein DZ, Ibrahim IM, Taghour MS, El-Mahdy HA, Ismail A, Alsfouk BA, Elkaeed EB, Metwaly AM, Eissa IH. El-Metwally SA, et al. Among authors: hagras m. RSC Adv. 2023 Aug 4;13(33):23365-23385. doi: 10.1039/d3ra03128d. eCollection 2023 Jul 26. RSC Adv. 2023. PMID: 37545598 Free PMC article.
71 results