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A PDX/Organoid Biobank of Advanced Prostate Cancers Captures Genomic and Phenotypic Heterogeneity for Disease Modeling and Therapeutic Screening.
Beshiri ML, Tice CM, Tran C, Nguyen HM, Sowalsky AG, Agarwal S, Jansson KH, Yang Q, McGowen KM, Yin J, Alilin AN, Karzai FH, Dahut WL, Corey E, Kelly K. Beshiri ML, et al. Among authors: tice cm. Clin Cancer Res. 2018 Sep 1;24(17):4332-4345. doi: 10.1158/1078-0432.CCR-18-0409. Epub 2018 May 10. Clin Cancer Res. 2018. PMID: 29748182 Free PMC article.
High-throughput screens identify HSP90 inhibitors as potent therapeutics that target inter-related growth and survival pathways in advanced prostate cancer.
Jansson KH, Tucker JB, Stahl LE, Simmons JK, Fuller C, Beshiri ML, Agarwal S, Fang L, Hynes PG, Alilin AN, Lake R, Abbey YC, Cawley J, Tice CM, Yin J, McKnight C, Klummp-Thomas C, Zhang X, Guha R, Hoover S, Simpson RM, Nguyen HM, Corey E, Thomas CJ, Proia DA, Kelly K. Jansson KH, et al. Among authors: tice cm. Sci Rep. 2018 Nov 22;8(1):17239. doi: 10.1038/s41598-018-35417-0. Sci Rep. 2018. PMID: 30467317 Free PMC article.
PROTAC-mediated Degradation of HIV-1 Nef Efficiently Restores Cell-surface CD4 and MHC-I Expression and Blocks HIV-1 Replication.
Emert-Sedlak LA, Tice CM, Shi H, Alvarado JJ, Shu ST, Reitz AB, Smithgall TE. Emert-Sedlak LA, et al. Among authors: tice cm. bioRxiv [Preprint]. 2023 Sep 5:2023.08.14.553289. doi: 10.1101/2023.08.14.553289. bioRxiv. 2023. Update in: Cell Chem Biol. 2024 Apr 18;31(4):658-668.e14. doi: 10.1016/j.chembiol.2024.02.004 PMID: 37645900 Free PMC article. Updated. Preprint.
Antiretroviral Drug Discovery Targeting the HIV-1 Nef Virulence Factor.
Emert-Sedlak LA, Shi H, Tice CM, Chen L, Alvarado JJ, Shu ST, Du S, Thomas CE, Wrobel JE, Reitz AB, Smithgall TE. Emert-Sedlak LA, et al. Among authors: tice cm. Viruses. 2022 Sep 13;14(9):2025. doi: 10.3390/v14092025. Viruses. 2022. PMID: 36146831 Free PMC article. Review.
Discovery of BI 135585, an in vivo efficacious oxazinanone-based 11β hydroxysteroid dehydrogenase type 1 inhibitor.
Zhuang L, Tice CM, Xu Z, Zhao W, Cacatian S, Ye YJ, Singh SB, Lindblom P, McKeever BM, Krosky PM, Zhao Y, Lala D, Kruk BA, Meng S, Howard L, Johnson JA, Bukhtiyarov Y, Panemangalore R, Guo J, Guo R, Himmelsbach F, Hamilton B, Schuler-Metz A, Schauerte H, Gregg R, McGeehan GM, Leftheris K, Claremon DA. Zhuang L, et al. Among authors: tice cm. Bioorg Med Chem. 2017 Jul 15;25(14):3649-3657. doi: 10.1016/j.bmc.2017.04.033. Epub 2017 Apr 29. Bioorg Med Chem. 2017. PMID: 28528082
Conformational control in structure-based drug design.
Zheng Y, Tice CM, Singh SB. Zheng Y, et al. Among authors: tice cm. Bioorg Med Chem Lett. 2017 Jul 1;27(13):2825-2837. doi: 10.1016/j.bmcl.2017.04.079. Epub 2017 Apr 27. Bioorg Med Chem Lett. 2017. PMID: 28479196 Review.
Brain penetrant liver X receptor (LXR) modulators based on a 2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole core.
Tice CM, Noto PB, Fan KY, Zhao W, Lotesta SD, Dong C, Marcus AP, Zheng YJ, Chen G, Wu Z, Van Orden R, Zhou J, Bukhtiyarov Y, Zhao Y, Lipinski K, Howard L, Guo J, Kandpal G, Meng S, Hardy A, Krosky P, Gregg RE, Leftheris K, McKeever BM, Singh SB, Lala D, McGeehan GM, Zhuang L, Claremon DA. Tice CM, et al. Bioorg Med Chem Lett. 2016 Oct 15;26(20):5044-5050. doi: 10.1016/j.bmcl.2016.08.089. Epub 2016 Aug 29. Bioorg Med Chem Lett. 2016. PMID: 27599745
35 results