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A trivalent mucosal vaccine encoding phylogenetically inferred ancestral RBD sequences confers pan-Sarbecovirus protection in mice.
Case JB, Sanapala S, Dillen C, Rhodes V, Zmasek C, Chicz TM, Switzer CE, Scheaffer SM, Georgiev G, Jacob-Dolan C, Hauser BM, Dos Anjos DCC, Adams LJ, Soudani N, Liang CY, Ying B, McNamara RP, Scheuermann RH, Boon ACM, Fremont DH, Whelan SPJ, Schmidt AG, Sette A, Grifoni A, Frieman MB, Diamond MS. Case JB, et al. Among authors: jacob dolan c. Cell Host Microbe. 2024 Nov 10:S1931-3128(24)00403-7. doi: 10.1016/j.chom.2024.10.016. Online ahead of print. Cell Host Microbe. 2024. PMID: 39561781 Free article.
SARS-CoV-2 XBB.1.5 mRNA booster vaccination elicits limited mucosal immunity.
Lasrado N, Rowe M, McMahan K, Hachmann NP, Miller J, Jacob-Dolan C, Liu J, Verrette B, Gotthardt KA, Ty DM, Pereira J, Mazurek CR, Hoyt A, Collier AY, Barouch DH. Lasrado N, et al. Among authors: jacob dolan c. Sci Transl Med. 2024 Oct 23;16(770):eadp8920. doi: 10.1126/scitranslmed.adp8920. Epub 2024 Oct 23. Sci Transl Med. 2024. PMID: 39441905 Free PMC article.
B cell somatic hypermutation following COVID-19 vaccination with Ad26.COV2.S.
Jacob-Dolan C, Lifton M, Powers OC, Miller J, Hachmann NP, Vu M, Surve N, Mazurek CR, Fisher JL, Rodrigues S, Patio RC, Anand T, Le Gars M, Sadoff J, Schmidt AG, Barouch DH. Jacob-Dolan C, et al. iScience. 2024 Apr 9;27(5):109716. doi: 10.1016/j.isci.2024.109716. eCollection 2024 May 17. iScience. 2024. PMID: 38655202 Free PMC article.
Comparison of the immunogenicity and protective efficacy of ACAM2000, MVA, and vectored subunit vaccines for Mpox in rhesus macaques.
Jacob-Dolan C, Ty D, Hope D, McMahan K, Liu J, Powers OC, Cotter CA, Sciacca M, Wu C, Borducchi E, Bouffard E, Richter H, Velasco J, Teow E, Boursiquot M, Cook A, Feliciano K, Yalley-Ogunro J, Seaman MS, Pessiant L, Lewis MG, Andersen H, Moss B, Barouch DH. Jacob-Dolan C, et al. Sci Transl Med. 2024 Mar 27;16(740):eadl4317. doi: 10.1126/scitranslmed.adl4317. Epub 2024 Mar 27. Sci Transl Med. 2024. PMID: 38536937
Mucosal boosting enhances vaccine protection against SARS-CoV-2 in macaques.
McMahan K, Wegmann F, Aid M, Sciacca M, Liu J, Hachmann NP, Miller J, Jacob-Dolan C, Powers O, Hope D, Wu C, Pereira J, Murdza T, Mazurek CR, Hoyt A, Boon ACM, Davis-Gardner M, Suthar MS, Martinot AJ, Boursiquot M, Cook A, Pessaint L, Lewis MG, Andersen H, Tolboom J, Serroyen J, Solforosi L, Costes LMM, Zahn RC, Barouch DH. McMahan K, et al. Among authors: jacob dolan c. Nature. 2024 Feb;626(7998):385-391. doi: 10.1038/s41586-023-06951-3. Epub 2023 Dec 14. Nature. 2024. PMID: 38096903 Free PMC article.
Mpox infection protects against re-challenge in rhesus macaques.
Aid M, Sciacca M, McMahan K, Hope D, Liu J, Jacob-Dolan C, Powers O, Barrett J, Wu C, Mutoni A, Murdza T, Richter H, Velasco J, Teow E, Boursiquot M, Cook A, Orekov T, Hamilton M, Pessaint L, Ryan A, Hayes T, Martinot AJ, Seaman MS, Lewis MG, Andersen H, Barouch DH. Aid M, et al. Among authors: jacob dolan c. Cell. 2023 Oct 12;186(21):4652-4661.e13. doi: 10.1016/j.cell.2023.08.023. Epub 2023 Sep 20. Cell. 2023. PMID: 37734373 Free PMC article.
SARS-CoV-2 RBD dimers elicit response comparable to VLPs in mice.
Love J, Rodriguez-Aponte S, Tostanoski L, Dalvie N, Johnston R, Jacob-Dolan C, Powers O, Hachmann N, Miller J, Hall K, Siamatu M, Mazurek C, Surve N, Barouch D. Love J, et al. Among authors: jacob dolan c. Res Sq [Preprint]. 2023 Apr 28:rs.3.rs-2692315. doi: 10.21203/rs.3.rs-2692315/v1. Res Sq. 2023. PMID: 37163131 Free PMC article. Preprint.
48 results