Chen QY - Search Results

1

VCP/p97 mediates nuclear targeting of non-ER-imported prion protein to maintain proteostasis.

Banik P, Ray K, Kamps J, Chen QY, Luesch H, Winklhofer KF, Tatzelt J. Banik P, et al. Among authors: chen qy. Life Sci Alliance. 2024 Apr 3;7(6):e202302456. doi: 10.26508/lsa.202302456. Print 2024 Jun. Life Sci Alliance. 2024. PMID: 38570188 Free PMC article.

2

Systematic Chemical Mutagenesis Identifies a Potent Novel Apratoxin A/E Hybrid with Improved in Vivo Antitumor Activity.

Chen QY, Liu Y, Luesch H. Chen QY, et al. ACS Med Chem Lett. 2011 Nov 10;2(11):861-865. doi: 10.1021/ml200176m. Epub 2011 Aug 31. ACS Med Chem Lett. 2011. PMID: 22081789 Free PMC article.

3

Largazole pharmacokinetics in rats by LC-MS/MS.

Yu M, Salvador LA, Sy SK, Tang Y, Singh RS, Chen QY, Liu Y, Hong J, Derendorf H, Luesch H. Yu M, et al. Among authors: chen qy. Mar Drugs. 2014 Mar 20;12(3):1623-40. doi: 10.3390/md12031623. Mar Drugs. 2014. PMID: 24658499 Free PMC article.

4

Improved total synthesis and biological evaluation of potent apratoxin S4 based anticancer agents with differential stability and further enhanced activity.

Chen QY, Liu Y, Cai W, Luesch H. Chen QY, et al. J Med Chem. 2014 Apr 10;57(7):3011-29. doi: 10.1021/jm4019965. Epub 2014 Mar 24. J Med Chem. 2014. PMID: 24660812 Free PMC article.

5

Evaluation of class I HDAC isoform selectivity of largazole analogues.

Kim B, Park H, Salvador LA, Serrano PE, Kwan JC, Zeller SL, Chen QY, Ryu S, Liu Y, Byeon S, Luesch H, Hong J. Kim B, et al. Among authors: chen qy. Bioorg Med Chem Lett. 2014 Aug 15;24(16):3728-31. doi: 10.1016/j.bmcl.2014.07.006. Epub 2014 Jul 9. Bioorg Med Chem Lett. 2014. PMID: 25070421 Free PMC article.

6

Modulation of Activity Profiles for Largazole-Based HDAC Inhibitors through Alteration of Prodrug Properties.

Salvador LA, Park H, Al-Awadhi FH, Liu Y, Kim B, Zeller SL, Chen QY, Hong J, Luesch H. Salvador LA, et al. Among authors: chen qy. ACS Med Chem Lett. 2014 Jul 7;5(8):905-10. doi: 10.1021/ml500170r. eCollection 2014 Aug 14. ACS Med Chem Lett. 2014. PMID: 25147612 Free PMC article.

7

Total Synthesis of the Potent Marine-Derived Elastase Inhibitor Lyngbyastatin 7 and in Vitro Biological Evaluation in Model Systems for Pulmonary Diseases.

Luo D, Chen QY, Luesch H. Luo D, et al. Among authors: chen qy. J Org Chem. 2016 Jan 15;81(2):532-44. doi: 10.1021/acs.joc.5b02386. Epub 2015 Dec 28. J Org Chem. 2016. PMID: 26709602 Free PMC article.

8

Total Synthesis and Biological Evaluation of Apratoxin E and Its C30 Epimer: Configurational Reassignment of the Natural Product.

Wu P, Cai W, Chen QY, Xu S, Yin R, Li Y, Zhang W, Luesch H. Wu P, et al. Among authors: chen qy. Org Lett. 2016 Oct 21;18(20):5400-5403. doi: 10.1021/acs.orglett.6b02780. Epub 2016 Oct 10. Org Lett. 2016. PMID: 27723359 Free PMC article.

9

Apratoxin S10, a Dual Inhibitor of Angiogenesis and Cancer Cell Growth To Treat Highly Vascularized Tumors.

Cai W, Chen QY, Dang LH, Luesch H. Cai W, et al. Among authors: chen qy. ACS Med Chem Lett. 2017 Sep 18;8(10):1007-1012. doi: 10.1021/acsmedchemlett.7b00192. eCollection 2017 Oct 12. ACS Med Chem Lett. 2017. PMID: 29057042 Free PMC article.

10

Correction to "Apratoxin S10, a Dual Inhibitor of Angiogenesis and Cancer Cell Growth To Treat Highly Vascularized Tumors".

Cai W, Chen QY, Dang LH, Luesch H. Cai W, et al. Among authors: chen qy. ACS Med Chem Lett. 2017 Dec 7;8(12):1342. doi: 10.1021/acsmedchemlett.7b00498. eCollection 2017 Dec 14. ACS Med Chem Lett. 2017. PMID: 29266134 Free PMC article.

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