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A novel inhibitory BAK antibody enables assessment of non-activated BAK in cancer cells.
Subas Satish HP, Iyer S, Shi MX, Wong AW, Fischer KC, Wardak AZ, Lio D, Brouwer JM, Uren RT, Czabotar PE, Miller MS, Kluck RM. Subas Satish HP, et al. Among authors: lio d. Cell Death Differ. 2024 Jun;31(6):711-721. doi: 10.1038/s41418-024-01289-3. Epub 2024 Apr 6. Cell Death Differ. 2024. PMID: 38582955 Free PMC article.
Structure of detergent-activated BAK dimers derived from the inert monomer.
Birkinshaw RW, Iyer S, Lio D, Luo CS, Brouwer JM, Miller MS, Robin AY, Uren RT, Dewson G, Kluck RM, Colman PM, Czabotar PE. Birkinshaw RW, et al. Among authors: lio d. Mol Cell. 2021 May 20;81(10):2123-2134.e5. doi: 10.1016/j.molcel.2021.03.014. Epub 2021 Mar 31. Mol Cell. 2021. PMID: 33794146 Free article.
Dynamic reconfiguration of pro-apoptotic BAK on membranes.
Sandow JJ, Tan IK, Huang AS, Masaldan S, Bernardini JP, Wardak AZ, Birkinshaw RW, Ninnis RL, Liu Z, Dalseno D, Lio D, Infusini G, Czabotar PE, Webb AI, Dewson G. Sandow JJ, et al. Among authors: lio d. EMBO J. 2021 Oct 18;40(20):e107237. doi: 10.15252/embj.2020107237. Epub 2021 Sep 15. EMBO J. 2021. PMID: 34523147 Free PMC article.
CSK-homologous kinase (CHK/MATK) is a potential colorectal cancer tumour suppressor gene epigenetically silenced by promoter methylation.
Chüeh AC, Advani G, Foroutan M, Smith J, Ng N, Nandurkar H, Lio DS, Zhu HJ, Chong YP, Verkade H, Fujita DJ, Bjorge J, Basheer F, Lim JP, Luk I, Dhillon A, Sakthianandeswaren A, Mouradov D, Sieber O, Hollande F, Mariadason JM, Cheng HC. Chüeh AC, et al. Among authors: lio ds. Oncogene. 2021 Apr;40(17):3015-3029. doi: 10.1038/s41388-021-01755-z. Epub 2021 Mar 25. Oncogene. 2021. PMID: 33767439
Activation of Src family tyrosine kinases by ferric ions.
Baldwin GS, Lio DS, Ferrand A, Catimel B, Shehan BP, Norton RS, Cheng HC. Baldwin GS, et al. Biochim Biophys Acta. 2014 Mar;1844(3):487-96. doi: 10.1016/j.bbapap.2013.12.004. Epub 2013 Dec 12. Biochim Biophys Acta. 2014. PMID: 24334106 Free article.
246 results