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Rag-GTPase-TFEB/TFE3 axis controls B cell mitochondrial fitness and humoral immunity independent of mTORC1.
Zhu X, Wu Y, Li Y, Zhou X, Watzlawik JO, Chen YM, Raybuck AL, Billadeau D, Shapiro V, Springer W, Sun J, Boothby MR, Zeng H. Zhu X, et al. Among authors: zeng h. Res Sq [Preprint]. 2024 Mar 29:rs.3.rs-3957355. doi: 10.21203/rs.3.rs-3957355/v1. Res Sq. 2024. Update in: Nat Commun. 2024 Nov 23;15(1):10163. doi: 10.1038/s41467-024-54344-5 PMID: 38585731 Free PMC article. Updated. Preprint.
Fatty acid metabolism in adaptive immunity.
Zhou X, Zhu X, Zeng H. Zhou X, et al. Among authors: zeng h. FEBS J. 2023 Feb;290(3):584-599. doi: 10.1111/febs.16296. Epub 2021 Dec 4. FEBS J. 2023. PMID: 34822226 Free PMC article. Review.
mTORC2 contributes to systemic autoimmunity.
Zhou X, Qi H, Li M, Li Y, Zhu X, Amin S, Alexander M, Diadhiou C, Davidson A, Zeng H. Zhou X, et al. Among authors: zeng h. Immunology. 2023 Mar;168(3):554-568. doi: 10.1111/imm.13594. Epub 2022 Nov 2. Immunology. 2023. PMID: 36273262 Free PMC article.
PP2A catalytic subunit alpha is critically required for CD8+ T cell homeostasis and anti-bacterial responses.
Zhou X, Li M, Ai M, Li Y, Zhu X, Hansen MJ, Zhong J, Johnson KL, Zenka R, Pandey A, Pease LR, Zeng H. Zhou X, et al. Among authors: zeng h. bioRxiv [Preprint]. 2024 Feb 9:2024.02.06.578745. doi: 10.1101/2024.02.06.578745. bioRxiv. 2024. Update in: Eur J Immunol. 2024 Oct;54(10):e2451080. doi: 10.1002/eji.202451080 PMID: 38370780 Free PMC article. Updated. Preprint.
The nutrient-sensing Rag-GTPase complex in B cells controls humoral immunity via TFEB/TFE3-dependent mitochondrial fitness.
Zhu X, Wu Y, Li Y, Zhou X, Watzlawik JO, Chen YM, Raybuck AL, Billadeau D, Shapiro V, Springer W, Sun J, Boothby MR, Zeng H. Zhu X, et al. Among authors: zeng h. bioRxiv [Preprint]. 2024 Mar 12:2024.02.26.582122. doi: 10.1101/2024.02.26.582122. bioRxiv. 2024. Update in: Nat Commun. 2024 Nov 23;15(1):10163. doi: 10.1038/s41467-024-54344-5 PMID: 38463988 Free PMC article. Updated. Preprint.
8,739 results