Izadi S - Search Results

1

Adapting Ferritin, a Naturally Occurring Protein Cage, to Modulate Intrinsic Agonism of OX40.

Shatz-Binder W, Azumaya CM, Leonard B, Vuong I, Sudhamsu J, Rohou A, Liu P, Sandoval W, Bol K, Izadi S, Holder PG, Blanchette C, Perozzo R, Kelley RF, Kalia Y. Shatz-Binder W, et al. Among authors: izadi s. Bioconjug Chem. 2024 May 15;35(5):593-603. doi: 10.1021/acs.bioconjchem.4c00020. Epub 2024 Apr 9. Bioconjug Chem. 2024. PMID: 38592684 Free PMC article.

2

Trehalose Limits Fragment Antibody Aggregation and Influences Charge Variant Formation in Spray-Dried Formulations at Elevated Temperatures.

Rajagopal K, Chang D, Nayak P, Izadi S, Patapoff T, Zhang J, Kelley R, Sreedhara A. Rajagopal K, et al. Among authors: izadi s. Mol Pharm. 2019 Jan 7;16(1):349-358. doi: 10.1021/acs.molpharmaceut.8b01002. Epub 2018 Dec 17. Mol Pharm. 2019. PMID: 30525659

3

Negative regulation of RAF kinase activity by ATP is overcome by 14-3-3-induced dimerization.

Liau NPD, Wendorff TJ, Quinn JG, Steffek M, Phung W, Liu P, Tang J, Irudayanathan FJ, Izadi S, Shaw AS, Malek S, Hymowitz SG, Sudhamsu J. Liau NPD, et al. Among authors: izadi s. Nat Struct Mol Biol. 2020 Feb;27(2):134-141. doi: 10.1038/s41594-019-0365-0. Epub 2020 Jan 27. Nat Struct Mol Biol. 2020. PMID: 31988522

4

Fc galactosylation follows consecutive reaction kinetics and enhances immunoglobulin G hexamerization for complement activation.

Wei B, Gao X, Cadang L, Izadi S, Liu P, Zhang HM, Hecht E, Shim J, Magill G, Pabon JR, Dai L, Phung W, Lin E, Wang C, Whang K, Sanchez S, Oropeza J Jr, Camperi J, Zhang J, Sandoval W, Zhang YT, Jiang G. Wei B, et al. Among authors: izadi s. MAbs. 2021 Jan-Dec;13(1):1893427. doi: 10.1080/19420862.2021.1893427. MAbs. 2021. PMID: 33682619 Free PMC article.

5

Structural basis for SHOC2 modulation of RAS signalling.

Liau NPD, Johnson MC, Izadi S, Gerosa L, Hammel M, Bruning JM, Wendorff TJ, Phung W, Hymowitz SG, Sudhamsu J. Liau NPD, et al. Among authors: izadi s. Nature. 2022 Sep;609(7926):400-407. doi: 10.1038/s41586-022-04838-3. Epub 2022 Jun 29. Nature. 2022. PMID: 35768504 Free PMC article.

6

Antibody-receptor interactions mediate antibody-dependent cellular cytotoxicity.

Sun Y, Izadi S, Callahan M, Deperalta G, Wecksler AT. Sun Y, et al. Among authors: izadi s. J Biol Chem. 2021 Jul;297(1):100826. doi: 10.1016/j.jbc.2021.100826. Epub 2021 May 24. J Biol Chem. 2021. PMID: 34044019 Free PMC article.

7

Probing the Protein-Excipient Interaction in the Orally Delivered Protein by Solid-State Hydrogen-Deuterium Exchange Mass Spectrometry and Molecular Dynamics.

Pan X, Lenka S, Davis J, Nagapudi K, Mantik P, Saggu M, Dai L, Cadang L, Zhang HM, Zhang J, Izadi S, Yang F, Wei B. Pan X, et al. Among authors: izadi s. Anal Chem. 2024 Jan 16;96(2):802-809. doi: 10.1021/acs.analchem.3c04255. Epub 2023 Dec 28. Anal Chem. 2024. PMID: 38155586

8

Modulation of the high concentration viscosity of IgG₁ antibodies using clinically validated Fc mutations.

Heisler J, Kovner D, Izadi S, Zarzar J, Carter PJ. Heisler J, et al. Among authors: izadi s. MAbs. 2024 Jan-Dec;16(1):2379560. doi: 10.1080/19420862.2024.2379560. Epub 2024 Jul 19. MAbs. 2024. PMID: 39028186 Free PMC article.

9

Variable domain mutational analysis to probe the molecular mechanisms of high viscosity of an IgG₁ antibody.

Dai J, Izadi S, Zarzar J, Wu P, Oh A, Carter PJ. Dai J, et al. Among authors: izadi s. MAbs. 2024 Jan-Dec;16(1):2304282. doi: 10.1080/19420862.2024.2304282. Epub 2024 Jan 25. MAbs. 2024. PMID: 38269489 Free PMC article.

10

Molecular surface descriptors to predict antibody developability: sensitivity to parameters, structure models, and conformational sampling.

Park E, Izadi S. Park E, et al. Among authors: izadi s. MAbs. 2024 Jan-Dec;16(1):2362788. doi: 10.1080/19420862.2024.2362788. Epub 2024 Jun 10. MAbs. 2024. PMID: 38853585 Free PMC article.

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