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Synthesis and in Vitro Cannabinoid Receptor 1 Activity of Recently Detected Synthetic Cannabinoids 4F-MDMB-BICA, 5F-MPP-PICA, MMB-4en-PICA, CUMYL-CBMICA, ADB-BINACA, APP-BINACA, 4F-MDMB-BINACA, MDMB-4en-PINACA, A-CHMINACA, 5F-AB-P7AICA, 5F-MDMB-P7AICA, and 5F-AP7AICA.
Cannaert A, Sparkes E, Pike E, Luo JL, Fang A, Kevin RC, Ellison R, Gerona R, Banister SD, Stove CP. Cannaert A, et al. Among authors: stove cp. ACS Chem Neurosci. 2020 Dec 16;11(24):4434-4446. doi: 10.1021/acschemneuro.0c00644. Epub 2020 Nov 30. ACS Chem Neurosci. 2020. PMID: 33253529
Systematic evaluation of a panel of 30 synthetic cannabinoid receptor agonists structurally related to MMB-4en-PICA, MDMB-4en-PINACA, ADB-4en-PINACA, and MMB-4CN-BUTINACA using a combination of binding and different CB1 receptor activation assays-Part II: Structure activity relationship assessment via a β-arrestin recruitment assay.
Grafinger KE, Cannaert A, Ametovski A, Sparkes E, Cairns E, Banister SD, Auwärter V, Stove CP. Grafinger KE, et al. Drug Test Anal. 2021 Jul;13(7):1402-1411. doi: 10.1002/dta.3035. Epub 2021 Apr 14. Drug Test Anal. 2021. PMID: 33769699
Systematic evaluation of a panel of 30 synthetic cannabinoid receptor agonists structurally related to MMB-4en-PICA, MDMB-4en-PINACA, ADB-4en-PINACA, and MMB-4CN-BUTINACA using a combination of binding and different CB1 receptor activation assays: Part I-Synthesis, analytical characterization, and binding affinity for human CB1 receptors.
Pike E, Grafinger KE, Cannaert A, Ametovski A, Luo JL, Sparkes E, Cairns EA, Ellison R, Gerona R, Stove CP, Auwärter V, Banister SD. Pike E, et al. Drug Test Anal. 2021 Jul;13(7):1383-1401. doi: 10.1002/dta.3037. Epub 2021 May 6. Drug Test Anal. 2021. PMID: 33787091
Systematic evaluation of a panel of 30 synthetic cannabinoid receptor agonists structurally related to MMB-4en-PICA, MDMB-4en-PINACA, ADB-4en-PINACA, and MMB-4CN-BUTINACA using a combination of binding and different CB1 receptor activation assays. Part III: The G protein pathway and critical comparison of different assays.
Grafinger KE, Vandeputte MM, Cannaert A, Ametovski A, Sparkes E, Cairns E, Juchli PO, Haschimi B, Pulver B, Banister SD, Stove CP, Auwärter V. Grafinger KE, et al. Drug Test Anal. 2021 Jul;13(7):1412-1429. doi: 10.1002/dta.3054. Epub 2021 May 21. Drug Test Anal. 2021. PMID: 33908179
NNL-3: A Synthetic Intermediate or a New Class of Hydroxybenzotriazole Esters with Cannabinoid Receptor Activity?
Ametovski A, Cairns EA, Grafinger KE, Cannaert A, Deventer MH, Chen S, Wu X, Shepperson CE, Lai F, Ellison R, Gerona R, Blakey K, Kevin R, McGregor IS, Hibbs DE, Glass M, Stove C, Auwärter V, Banister SD. Ametovski A, et al. Among authors: stove c. ACS Chem Neurosci. 2021 Nov 3;12(21):4020-4036. doi: 10.1021/acschemneuro.1c00348. Epub 2021 Oct 22. ACS Chem Neurosci. 2021. PMID: 34676751
Structure-activity relationships of valine, tert-leucine, and phenylalanine amino acid-derived synthetic cannabinoid receptor agonists related to ADB-BUTINACA, APP-BUTINACA, and ADB-P7AICA.
Sparkes E, Cairns EA, Kevin RC, Lai F, Grafinger KE, Chen S, Deventer MH, Ellison R, Boyd R, Martin LJ, McGregor IS, Gerona RR, Hibbs DE, Auwärter V, Glass M, Stove C, Banister SD. Sparkes E, et al. Among authors: stove c. RSC Med Chem. 2021 Oct 25;13(2):156-174. doi: 10.1039/d1md00242b. eCollection 2022 Feb 23. RSC Med Chem. 2021. PMID: 35308023 Free PMC article.
258 results