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ATF3 and CH25H regulate effector trogocytosis and anti-tumor activities of endogenous and immunotherapeutic cytotoxic T lymphocytes.
Lu Z, McBrearty N, Chen J, Tomar VS, Zhang H, De Rosa G, Tan A, Weljie AM, Beiting DP, Miao Z, George SS, Berger A, Saggu G, Diehl JA, Koumenis C, Fuchs SY. Lu Z, et al. Among authors: beiting dp. Cell Metab. 2024 May 7;36(5):1164-1167. doi: 10.1016/j.cmet.2024.04.002. Epub 2024 Apr 11. Cell Metab. 2024. PMID: 38604169 No abstract available.
PARP11 inhibition inactivates tumor-infiltrating regulatory T cells and improves the efficacy of immunotherapies.
Basavaraja R, Zhang H, Holczbauer Á, Lu Z, Radaelli E, Assenmacher CA, George SS, Nallamala VC, Beiting DP, Meyer-Ficca ML, Meyer RG, Guo W, Fan Y, Modzelewski AJ, Spiegelman VS, Cohen MS, Fuchs SY. Basavaraja R, et al. Among authors: beiting dp. Cell Rep Med. 2024 Jul 16;5(7):101649. doi: 10.1016/j.xcrm.2024.101649. Cell Rep Med. 2024. PMID: 39019005 Free PMC article.
Maintenance of X chromosome inactivation after T cell activation requires NF-κB signaling.
Forsyth KS, Toothacre NE, Jiwrajka N, Driscoll AM, Shallberg LA, Cunningham-Rundles C, Barmettler S, Farmer J, Verbsky J, Routes J, Beiting DP, Romberg N, May MJ, Anguera MC. Forsyth KS, et al. Among authors: beiting dp. Sci Immunol. 2024 Oct 4;9(100):eado0398. doi: 10.1126/sciimmunol.ado0398. Epub 2024 Oct 4. Sci Immunol. 2024. PMID: 39365876
Modified C-type natriuretic peptide normalizes tumor vasculature, reinvigorates antitumor immunity, and improves solid tumor therapies.
Lu Z, Verginadis I, Kumazoe M, Castillo GM, Yao Y, Guerra RE, Bicher S, You M, McClung G, Qiu R, Xiao Z, Miao Z, George SS, Beiting DP, Nojiri T, Tanaka Y, Fujimura Y, Onda H, Hatakeyama Y, Nishimoto-Ashfield A, Bykova K, Guo W, Fan Y, Buynov NM, Diehl JA, Stanger BZ, Tachibana H, Gade TP, Puré E, Koumenis C, Bolotin EM, Fuchs SY. Lu Z, et al. Among authors: beiting dp. Sci Transl Med. 2024 Aug 21;16(761):eadn0904. doi: 10.1126/scitranslmed.adn0904. Epub 2024 Aug 21. Sci Transl Med. 2024. PMID: 39167664
Transcriptional control of the Cryptosporidium life cycle.
Walzer KA, Tandel J, Byerly JH, Daniels AM, Gullicksrud JA, Whelan EC, Carro SD, Krespan E, Beiting DP, Striepen B. Walzer KA, et al. Among authors: beiting dp. Nature. 2024 Jun;630(8015):174-180. doi: 10.1038/s41586-024-07466-1. Epub 2024 May 29. Nature. 2024. PMID: 38811723
NF-κB Signaling is Required for X-Chromosome Inactivation Maintenance Following T cell Activation.
Forsyth KS, Toothacre NE, Jiwrajka N, Driscoll AM, Shallberg LA, Cunningham-Rundles C, Barmettler S, Farmer J, Verbsky J, Routes J, Beiting DP, Romberg N, May MJ, Anguera MC. Forsyth KS, et al. Among authors: beiting dp. bioRxiv [Preprint]. 2024 Feb 12:2024.02.08.579505. doi: 10.1101/2024.02.08.579505. bioRxiv. 2024. PMID: 38405871 Free PMC article. Preprint.
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