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A call for accessible tools to unlock single-cell immunometabolism research.
Cosgrove J, Marçais A, Hartmann FJ, Bergthaler A, Zanoni I, Corrado M, Perié L, Cabezas-Wallscheid N, Bousso P, Alexandrov T, Kielian T, Martínez-Martín N, Opitz CA, Lyssiotis CA, Argüello RJ, Van den Bossche J. Cosgrove J, et al. Among authors: opitz ca. Nat Metab. 2024 May;6(5):779-782. doi: 10.1038/s42255-024-01031-w. Nat Metab. 2024. PMID: 38605184 Free article. No abstract available.
Hepatocyte-intrinsic type I interferon signaling reprograms metabolism and reveals a novel compensatory mechanism of the tryptophan-kynurenine pathway in viral hepatitis.
Lercher A, Popa AM, Viczenczova C, Kosack L, Klavins K, Agerer B, Opitz CA, Lanz TV, Platten M, Bergthaler A. Lercher A, et al. Among authors: opitz ca. PLoS Pathog. 2020 Oct 12;16(10):e1008973. doi: 10.1371/journal.ppat.1008973. eCollection 2020 Oct. PLoS Pathog. 2020. PMID: 33045014 Free PMC article.
Glutarate tunes T cell fate.
Yanqui-Rivera F, Opitz CA. Yanqui-Rivera F, et al. Among authors: opitz ca. Nat Metab. 2023 Oct;5(10):1649-1651. doi: 10.1038/s42255-023-00878-9. Nat Metab. 2023. PMID: 37605056 No abstract available.
An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor.
Opitz CA, Litzenburger UM, Sahm F, Ott M, Tritschler I, Trump S, Schumacher T, Jestaedt L, Schrenk D, Weller M, Jugold M, Guillemin GJ, Miller CL, Lutz C, Radlwimmer B, Lehmann I, von Deimling A, Wick W, Platten M. Opitz CA, et al. Nature. 2011 Oct 5;478(7368):197-203. doi: 10.1038/nature10491. Nature. 2011. PMID: 21976023 Free article.
Spatial probabilistic mapping of metabolite ensembles in mass spectrometry imaging.
Abu Sammour D, Cairns JL, Boskamp T, Marsching C, Kessler T, Ramallo Guevara C, Panitz V, Sadik A, Cordes J, Schmidt S, Mohammed SA, Rittel MF, Friedrich M, Platten M, Wolf I, von Deimling A, Opitz CA, Wick W, Hopf C. Abu Sammour D, et al. Among authors: opitz ca. Nat Commun. 2023 Apr 1;14(1):1823. doi: 10.1038/s41467-023-37394-z. Nat Commun. 2023. PMID: 37005414 Free PMC article.
Dietary tryptophan links encephalogenicity of autoreactive T cells with gut microbial ecology.
Sonner JK, Keil M, Falk-Paulsen M, Mishra N, Rehman A, Kramer M, Deumelandt K, Röwe J, Sanghvi K, Wolf L, von Landenberg A, Wolff H, Bharti R, Oezen I, Lanz TV, Wanke F, Tang Y, Brandao I, Mohapatra SR, Epping L, Grill A, Röth R, Niesler B, Meuth SG, Opitz CA, Okun JG, Reinhardt C, Kurschus FC, Wick W, Bode HB, Rosenstiel P, Platten M. Sonner JK, et al. Among authors: opitz ca. Nat Commun. 2019 Oct 25;10(1):4877. doi: 10.1038/s41467-019-12776-4. Nat Commun. 2019. PMID: 31653831 Free PMC article.
Heterogeneity of response to immune checkpoint blockade in hypermutated experimental gliomas.
Aslan K, Turco V, Blobner J, Sonner JK, Liuzzi AR, Núñez NG, De Feo D, Kickingereder P, Fischer M, Green E, Sadik A, Friedrich M, Sanghvi K, Kilian M, Cichon F, Wolf L, Jähne K, von Landenberg A, Bunse L, Sahm F, Schrimpf D, Meyer J, Alexander A, Brugnara G, Röth R, Pfleiderer K, Niesler B, von Deimling A, Opitz C, Breckwoldt MO, Heiland S, Bendszus M, Wick W, Becher B, Platten M. Aslan K, et al. Nat Commun. 2020 Feb 18;11(1):931. doi: 10.1038/s41467-020-14642-0. Nat Commun. 2020. PMID: 32071302 Free PMC article.
Making liver cancer cells go ARGh!
Henneberg AL, Opitz CA. Henneberg AL, et al. Among authors: opitz ca. EMBO J. 2022 Nov 2;41(21):e112415. doi: 10.15252/embj.2022112415. Epub 2022 Oct 12. EMBO J. 2022. PMID: 36222348 Free PMC article.
64 results