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Microbiota-derived inosine programs protective CD8+ T cell responses against influenza in newborns.
Stevens J, Culberson E, Kinder J, Ramiriqui A, Gray J, Bonfield M, Shao TY, Al Gharabieh F, Peterson L, Steinmeyer S, Zacharias W, Pryhuber G, Paul O, Sengupta S, Alenghat T, Way SS, Deshmukh H. Stevens J, et al. Among authors: deshmukh h. bioRxiv [Preprint]. 2024 Apr 13:2024.04.09.588427. doi: 10.1101/2024.04.09.588427. bioRxiv. 2024. PMID: 38645130 Free PMC article. Preprint.
The balance between protective and pathogenic immune responses to pneumonia in the neonatal lung is enforced by gut microbiota.
Stevens J, Steinmeyer S, Bonfield M, Peterson L, Wang T, Gray J, Lewkowich I, Xu Y, Du Y, Guo M, Wynn JL, Zacharias W, Salomonis N, Miller L, Chougnet C, O'Connor DH, Deshmukh H. Stevens J, et al. Among authors: deshmukh h. Sci Transl Med. 2022 Jun 15;14(649):eabl3981. doi: 10.1126/scitranslmed.abl3981. Epub 2022 Jun 15. Sci Transl Med. 2022. PMID: 35704600 Free PMC article.
Inflammatory blockade prevents injury to the developing pulmonary gas exchange surface in preterm primates.
Toth A, Steinmeyer S, Kannan P, Gray J, Jackson CM, Mukherjee S, Demmert M, Sheak JR, Benson D, Kitzmiller J, Wayman JA, Presicce P, Cates C, Rubin R, Chetal K, Du Y, Miao Y, Gu M, Guo M, Kalinichenko VV, Kallapur SG, Miraldi ER, Xu Y, Swarr D, Lewkowich I, Salomonis N, Miller L, Sucre JS, Whitsett JA, Chougnet CA, Jobe AH, Deshmukh H, Zacharias WJ. Toth A, et al. Among authors: deshmukh h. Sci Transl Med. 2022 Mar 30;14(638):eabl8574. doi: 10.1126/scitranslmed.abl8574. Epub 2022 Mar 30. Sci Transl Med. 2022. PMID: 35353543 Free PMC article.
A potent myeloid response is rapidly activated in the lungs of premature Rhesus macaques exposed to intra-uterine inflammation.
Jackson CM, Demmert M, Mukherjee S, Isaacs T, Thompson R, Chastain C, Gray J, Senthamaraikannan P, Presicce P, Chetal K, Salomonis N, Miller LA, Jobe AH, Kallapur SG, Zacharias WJ, Lewkowich IP, Deshmukh H, Chougnet CA. Jackson CM, et al. Among authors: deshmukh h. Mucosal Immunol. 2022 Apr;15(4):730-744. doi: 10.1038/s41385-022-00495-x. Epub 2022 Mar 21. Mucosal Immunol. 2022. PMID: 35314757 Free PMC article.
Delayed Microbial Maturation Durably Exacerbates Th17-driven Asthma in Mice.
Wilburn AN, McAlees JW, Haslam DB, Graspeuntner S, Schmudde I, Laumonnier Y, Rupp J, Chougnet CA, Deshmukh H, Zacharias WJ, König P, Lewkowich IP. Wilburn AN, et al. Among authors: deshmukh h. Am J Respir Cell Mol Biol. 2023 May;68(5):498-510. doi: 10.1165/rcmb.2022-0367OC. Am J Respir Cell Mol Biol. 2023. PMID: 36622830 Free PMC article.
234 results