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CD4+ T cells reactive to a hybrid peptide from insulin-chromogranin A adopt a distinct effector fate and are pathogenic in autoimmune diabetes.
Mitchell JS, Spanier JA, Dwyer AJ, Knutson TP, Alkhatib MH, Qian G, Weno ME, Chen Y, Shaheen ZR, Tucker CG, Kangas TO, Morales MS, Silva N, Kaisho T, Farrar MA, Fife BT. Mitchell JS, et al. Among authors: fife bt. Immunity. 2024 Oct 8;57(10):2399-2415.e8. doi: 10.1016/j.immuni.2024.07.024. Epub 2024 Aug 29. Immunity. 2024. PMID: 39214091
Antigen-specific T cell responses in autoimmune diabetes.
Dwyer AJ, Shaheen ZR, Fife BT. Dwyer AJ, et al. Among authors: fife bt. Front Immunol. 2024 Aug 15;15:1440045. doi: 10.3389/fimmu.2024.1440045. eCollection 2024. Front Immunol. 2024. PMID: 39211046 Free PMC article. Review.
Insulin B peptide-MHC class II-specific chimeric antigen receptor-Tregs prevent autoimmune diabetes.
Spanier JA, Fung V, Wardell CM, Alkhatib MH, Chen Y, Swanson LA, Dwyer AJ, Weno ME, Silva N, Mitchell JS, Orban PC, Mojibian M, Verchere CB, Fife BT, Levings MK. Spanier JA, et al. Among authors: fife bt. bioRxiv [Preprint]. 2023 Feb 24:2023.02.23.529737. doi: 10.1101/2023.02.23.529737. bioRxiv. 2023. Update in: J Clin Invest. 2023 Sep 15;133(18):e168601. doi: 10.1172/JCI168601 PMID: 36865264 Free PMC article. Updated. Preprint.
Evaluating the Immunopathogenesis of Diabetes After Acute Pancreatitis in the Diabetes RElated to Acute Pancreatitis and Its Mechanisms Study: From the Type 1 Diabetes in Acute Pancreatitis Consortium.
Casu A, Grippo PJ, Wasserfall C, Sun Z, Linsley PS, Hamerman JA, Fife BT, Lacy-Hulbert A, Toledo FGS, Hart PA, Papachristou GI, Bellin MD, Yadav D, Laughlin MR, Goodarzi MO, Speake C; Type 1 Diabetes in Acute Pancreatitis Consortium (T1DAPC). Casu A, et al. Among authors: fife bt. Pancreas. 2022 Jul 1;51(6):580-585. doi: 10.1097/MPA.0000000000002076. Pancreas. 2022. PMID: 36206462 Free PMC article.
The Role of Programmed Death-1 in Type 1 Diabetes.
Tucker CG, Dwyer AJ, Fife BT, Martinov T. Tucker CG, et al. Among authors: fife bt. Curr Diab Rep. 2021 May 6;21(6):20. doi: 10.1007/s11892-021-01384-6. Curr Diab Rep. 2021. PMID: 33956235 Free PMC article. Review.
72 results