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MYBPC3-c.772G>A mutation results in haploinsufficiency and altered myosin cycling kinetics in a patient induced stem cell derived cardiomyocyte model of hypertrophic cardiomyopathy.
Steczina S, Mohran S, Bailey LRJ, McMillen TS, Kooiker KB, Wood NB, Davis J, Previs MJ, Olivotto I, Pioner JM, Geeves MA, Poggesi C, Regnier M. Steczina S, et al. Among authors: poggesi c. J Mol Cell Cardiol. 2024 Jun;191:27-39. doi: 10.1016/j.yjmcc.2024.04.010. Epub 2024 Apr 20. J Mol Cell Cardiol. 2024. PMID: 38648963
Impaired diastolic function after exchange of endogenous troponin I with C-terminal truncated troponin I in human cardiac muscle.
Narolska NA, Piroddi N, Belus A, Boontje NM, Scellini B, Deppermann S, Zaremba R, Musters RJ, dos Remedios C, Jaquet K, Foster DB, Murphy AM, van Eyk JE, Tesi C, Poggesi C, van der Velden J, Stienen GJ. Narolska NA, et al. Among authors: poggesi c. Circ Res. 2006 Oct 27;99(9):1012-20. doi: 10.1161/01.RES.0000248753.30340.af. Epub 2006 Oct 5. Circ Res. 2006. PMID: 17023673
HDAC6 contributes to pathological responses of heart and skeletal muscle to chronic angiotensin-II signaling.
Demos-Davies KM, Ferguson BS, Cavasin MA, Mahaffey JH, Williams SM, Spiltoir JI, Schuetze KB, Horn TR, Chen B, Ferrara C, Scellini B, Piroddi N, Tesi C, Poggesi C, Jeong MY, McKinsey TA. Demos-Davies KM, et al. Among authors: poggesi c. Am J Physiol Heart Circ Physiol. 2014 Jul 15;307(2):H252-8. doi: 10.1152/ajpheart.00149.2014. Epub 2014 May 23. Am J Physiol Heart Circ Physiol. 2014. PMID: 24858848 Free PMC article.
Tropomyosin Ser-283 pseudo-phosphorylation slows myofibril relaxation.
Nixon BR, Liu B, Scellini B, Tesi C, Piroddi N, Ogut O, Solaro RJ, Ziolo MT, Janssen PM, Davis JP, Poggesi C, Biesiadecki BJ. Nixon BR, et al. Among authors: poggesi c. Arch Biochem Biophys. 2013 Jul 1;535(1):30-8. doi: 10.1016/j.abb.2012.11.010. Epub 2012 Dec 8. Arch Biochem Biophys. 2013. PMID: 23232082 Free PMC article.
134 results