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Page 1
Cognitive reserve against Alzheimer's pathology is linked to brain activity during memory formation.
Vockert N, Machts J, Kleineidam L, Nemali A, Incesoy EI, Bernal J, Schütze H, Yakupov R, Peters O, Gref D, Schneider LS, Preis L, Priller J, Spruth EJ, Altenstein S, Schneider A, Fliessbach K, Wiltfang J, Rostamzadeh A, Glanz W, Teipel S, Kilimann I, Goerss D, Laske C, Munk MH, Spottke A, Roy N, Heneka MT, Brosseron F, Wagner M, Wolfsgruber S, Dobisch L, Dechent P, Hetzer S, Scheffler K, Zeidman P, Stern Y, Schott BH, Jessen F, Düzel E, Maass A, Ziegler G; DELCODE study group. Vockert N, et al. Among authors: kleineidam l. Nat Commun. 2024 Nov 13;15(1):9815. doi: 10.1038/s41467-024-53360-9. Nat Commun. 2024. PMID: 39537609 Free PMC article.
Association of Neurogranin and BACE1 With Clinical Cognitive Decline in Individuals With Subjective Cognitive Decline.
Wang X, Freiesleben SD, Schneider LS, Preis L, Priller J, Spruth EJ, Altenstein S, Schneider A, Fliessbach K, Wiltfang J, Hansen N, Jessen F, Rostamzadeh A, Duzel E, Glanz W, Incesoy EI, Buerger K, Janowitz D, Ewers M, Perneczky R, Rauchmann BS, Teipel SJ, Kilimann I, Goerss D, Laske C, Munk MHJ, Spottke A, Roy-Kluth N, Heneka MT, Brosseron F, Wagner M, Wolfsgruber S, Ramirez A, Kleineidam L, Stark M, Peters O. Wang X, et al. Among authors: kleineidam l. Neurology. 2024 Oct 22;103(8):e209806. doi: 10.1212/WNL.0000000000209806. Epub 2024 Sep 20. Neurology. 2024. PMID: 39303184
Prognostic value of Alzheimer's disease plasma biomarkers in the oldest-old: a prospective primary care-based study.
Martino-Adami PV, Chatterjee M, Kleineidam L, Weyerer S, Bickel H, Wiese B, Riedel-Heller SG, Scherer M, Blennow K, Zetterberg H, Wagner M, Schneider A, Ramirez A. Martino-Adami PV, et al. Among authors: kleineidam l. Lancet Reg Health Eur. 2024 Aug 16;45:101030. doi: 10.1016/j.lanepe.2024.101030. eCollection 2024 Oct. Lancet Reg Health Eur. 2024. PMID: 39253733 Free PMC article.
Amyloid and SCD jointly predict cognitive decline across Chinese and German cohorts.
Shao K, Hu X, Kleineidam L, Stark M, Altenstein S, Amthauer H, Boecker H, Buchert R, Buerger K, Butryn M, Cai Y, Cai Y, Cosma NC, Chen G, Chen Z, Daamen M, Drzezga A, Düzel E, Essler M, Ewers M, Fliessbach K, Gaertner FC, Glanz W, Guo T, Hansen N, He B, Janowitz D, Kilimann I, Krause BJ, Lan G, Lange C, Laske C, Li Y, Li R, Liu L, Lu J, Meng F, Munk MH, Peters O, Perneczky R, Priller J, Ramirez A, Rauchmann BS, Reimold M, Rominger A, Rostamzadeh A, Roy-Kluth N, Schneider A, Spottke A, Spruth EJ, Sun P, Teipel S, Wang X, Wei M, Wei Y, Wiltfang J, Yan S, Yang J, Yu X, Zhang M, Zhang L; DELCODE study group, SILCODE study group; Wagner M, Jessen F, Han Y, Kuhn E. Shao K, et al. Among authors: kleineidam l. Alzheimers Dement. 2024 Sep;20(9):5926-5939. doi: 10.1002/alz.14119. Epub 2024 Jul 27. Alzheimers Dement. 2024. PMID: 39072956 Free PMC article.
Plasma amyloid beta X-42/X-40 ratio and cognitive decline in suspected early and preclinical Alzheimer's disease.
Vogelgsang J, Hansen N, Stark M, Wagner M, Klafki H, Morgado BM, Jahn-Brodmann A, Schott B, Esselmann H, Bauer C, Schuchhardt J, Kleineidam L, Wolfsgruber S, Peters O, Schneider LS, Wang X, Menne F, Priller J, Spruth E, Altenstein S, Lohse A, Schneider A, Fliessbach K, Vogt I, Bartels C, Jessen F, Rostamzadeh A, Duezel E, Glanz W, Incesoy E, Butryn M, Buerger K, Janowitz D, Ewers M, Perneczky R, Rauchmann B, Guersel S, Teipel S, Kilimann I, Goerss D, Laske C, Munk M, Sanzenbacher C, Spottke A, Roy-Kluth N, Heneka M, Brosseron F, Ramierez A, Schmid M, Wiltfang J. Vogelgsang J, et al. Among authors: kleineidam l. Alzheimers Dement. 2024 Aug;20(8):5132-5142. doi: 10.1002/alz.13909. Epub 2024 Jun 28. Alzheimers Dement. 2024. PMID: 38940303 Free PMC article.
Age-specific risk factors of depression among the oldest-old - evidence from the multicenter AgeCoDe-AgeQualiDe study.
Luppa M, Pabst A, Löbner M, Mallon T, Brettschneider C, Hajek A, Heser K, Kleineidam L, Weyerer S, Werle J, Pentzek M, Weeg D, Mösch E, Wiese B, Oey A, Wagner M, Maier W, Scherer M, König HH, Riedel-Heller SG. Luppa M, et al. Among authors: kleineidam l. Front Psychiatry. 2024 Jun 11;15:1367225. doi: 10.3389/fpsyt.2024.1367225. eCollection 2024. Front Psychiatry. 2024. PMID: 38919640 Free PMC article.
Plasma extracellular vesicle tau and TDP-43 as diagnostic biomarkers in FTD and ALS.
Chatterjee M, Özdemir S, Fritz C, Möbius W, Kleineidam L, Mandelkow E, Biernat J, Doğdu C, Peters O, Cosma NC, Wang X, Schneider LS, Priller J, Spruth E, Kühn AA, Krause P, Klockgether T, Vogt IR, Kimmich O, Spottke A, Hoffmann DC, Fliessbach K, Miklitz C, McCormick C, Weydt P, Falkenburger B, Brandt M, Guenther R, Dinter E, Wiltfang J, Hansen N, Bähr M, Zerr I, Flöel A, Nestor PJ, Düzel E, Glanz W, Incesoy E, Bürger K, Janowitz D, Perneczky R, Rauchmann BS, Hopfner F, Wagemann O, Levin J, Teipel S, Kilimann I, Goerss D, Prudlo J, Gasser T, Brockmann K, Mengel D, Zimmermann M, Synofzik M, Wilke C, Selma-González J, Turon-Sans J, Santos-Santos MA, Alcolea D, Rubio-Guerra S, Fortea J, Carbayo Á, Lleó A, Rojas-García R, Illán-Gala I, Wagner M, Frommann I, Roeske S, Bertram L, Heneka MT, Brosseron F, Ramirez A, Schmid M, Beschorner R, Halle A, Herms J, Neumann M, Barthélemy NR, Bateman RJ, Rizzu P, Heutink P, Dols-Icardo O, Höglinger G, Hermann A, Schneider A. Chatterjee M, et al. Among authors: kleineidam l. Nat Med. 2024 Jun;30(6):1771-1783. doi: 10.1038/s41591-024-02937-4. Epub 2024 Jun 18. Nat Med. 2024. PMID: 38890531 Free PMC article.
Symptomatic Clusters Related to Amyloid Positivity in Cognitively Unimpaired Individuals.
Sannemann L, Bartels C, Brosseron F, Buerger K, Fliessbach K, Freiesleben SD, Frommann I, Glanz W, Heneka MT, Janowitz D, Kilimann I, Kleineidam L, Lammerding D, Laske C, Munk MHJ, Perneczky R, Peters O, Priller J, Rauchmann BS, Rostamzadeh A, Roy-Kluth N, Schild AK, Schneider A, Schneider LS, Spottke A, Spruth EJ, Teipel S, Wagner M, Wiltfang J, Wolfsgruber S, Duezel E, Jessen F; DELCODE Study Group. Sannemann L, et al. Among authors: kleineidam l. J Alzheimers Dis. 2024;100(1):193-205. doi: 10.3233/JAD-231335. J Alzheimers Dis. 2024. PMID: 38848176
Single-value brain activity scores reflect both severity and risk across the Alzheimer's continuum.
Soch J, Richter A, Kizilirmak JM, Schütze H, Ziegler G, Altenstein S, Brosseron F, Dechent P, Fliessbach K, Freiesleben SD, Glanz W, Gref D, Heneka MT, Hetzer S, Incesoy EI, Kilimann I, Kimmich O, Kleineidam L, Kuhn E, Laske C, Lohse A, Lüsebrink F, Munk MH, Peters O, Preis L, Priller J, Ramirez A, Roeske S, Rostamzadeh A, Roy-Kluth N, Scheffler K, Schmid M, Schneider A, Spottke A, Spruth EJ, Teipel S, Wiltfang J, Jessen F, Wagner M, Düzel E, Schott BH. Soch J, et al. Among authors: kleineidam l. Brain. 2024 Nov 4;147(11):3789-3803. doi: 10.1093/brain/awae149. Brain. 2024. PMID: 38743817 Free PMC article.
Inferior Frontal Sulcal Hyperintensities on Brain MRI Are Associated with Amyloid Positivity beyond Age-Results from the Multicentre Observational DELCODE Study.
Dörner M, Seebach K, Heneka MT, Menze I, von Känel R, Euler S, Schreiber F, Arndt P, Neumann K, Hildebrand A, John AC, Tyndall A, Kirchebner J, Tacik P, Jansen R, Grimm A, Henneicke S, Perosa V, Meuth SG, Peters O, Hellmann-Regen J, Preis L, Priller J, Spruth EJ, Schneider A, Fliessbach K, Wiltfang J, Jessen F, Rostamzadeh A, Glanz W, Schulze JB, Schiebler SLF, Buerger K, Janowitz D, Perneczky R, Rauchmann BS, Teipel S, Kilimann I, Laske C, Munk MH, Spottke A, Roy-Kluth N, Wagner M, Frommann I, Lüsebrink F, Dechent P, Hetzer S, Scheffler K, Kleineidam L, Stark M, Schmid M, Ersözlü E, Brosseron F, Ewers M, Schott BH, Düzel E, Ziegler G, Mattern H, Schreiber S, Bernal J. Dörner M, et al. Among authors: kleineidam l. Diagnostics (Basel). 2024 Apr 30;14(9):940. doi: 10.3390/diagnostics14090940. Diagnostics (Basel). 2024. PMID: 38732354 Free PMC article.
89 results