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Page 1
Oncogene-induced matrix reorganization controls CD8+ T cell function in the soft-tissue sarcoma microenvironment.
Fuller AM, Pruitt HC, Liu Y, Irizarry-Negron VM, Pan H, Song H, DeVine A, Katti RS, Devalaraja S, Ciotti GE, Gonzalez MV, Williams EF, Murazzi I, Ntekoumes D, Skuli N, Hakonarson H, Zabransky DJ, Trevino JG, Weeraratna A, Weber K, Haldar M, Fraietta JA, Gerecht S, Eisinger-Mathason TSK. Fuller AM, et al. Among authors: ciotti ge. J Clin Invest. 2024 Apr 23;134(11):e167826. doi: 10.1172/JCI167826. J Clin Invest. 2024. PMID: 38652549 Free PMC article.
TGFβ and Hippo Pathways Cooperate to Enhance Sarcomagenesis and Metastasis through the Hyaluronan-Mediated Motility Receptor (HMMR).
Ye S, Liu Y, Fuller AM, Katti R, Ciotti GE, Chor S, Alam MZ, Devalaraja S, Lorent K, Weber K, Haldar M, Pack MA, Eisinger-Mathason TSK. Ye S, et al. Among authors: ciotti ge. Mol Cancer Res. 2020 Apr;18(4):560-573. doi: 10.1158/1541-7786.MCR-19-0877. Epub 2020 Jan 27. Mol Cancer Res. 2020. PMID: 31988250 Free PMC article.
Hypoxia and the Tumor Secretome.
Liu Y, Ciotti GE, Eisinger-Mathason TSK. Liu Y, et al. Among authors: ciotti ge. Adv Exp Med Biol. 2019;1136:57-69. doi: 10.1007/978-3-030-12734-3_4. Adv Exp Med Biol. 2019. PMID: 31201716 Review.
Tumor-Derived Retinoic Acid Regulates Intratumoral Monocyte Differentiation to Promote Immune Suppression.
Devalaraja S, To TKJ, Folkert IW, Natesan R, Alam MZ, Li M, Tada Y, Budagyan K, Dang MT, Zhai L, Lobel GP, Ciotti GE, Eisinger-Mathason TSK, Asangani IA, Weber K, Simon MC, Haldar M. Devalaraja S, et al. Among authors: ciotti ge. Cell. 2020 Mar 19;180(6):1098-1114.e16. doi: 10.1016/j.cell.2020.02.042. Epub 2020 Mar 12. Cell. 2020. PMID: 32169218 Free PMC article.
YAP1-Mediated Suppression of USP31 Enhances NFκB Activity to Promote Sarcomagenesis.
Ye S, Lawlor MA, Rivera-Reyes A, Egolf S, Chor S, Pak K, Ciotti GE, Lee AC, Marino GE, Shah J, Niedzwicki D, Weber K, Park PMC, Alam MZ, Grazioli A, Haldar M, Xu M, Perry JA, Qi J, Eisinger-Mathason TSK. Ye S, et al. Among authors: ciotti ge. Cancer Res. 2018 May 15;78(10):2705-2720. doi: 10.1158/0008-5472.CAN-17-4052. Epub 2018 Feb 28. Cancer Res. 2018. PMID: 29490948 Free PMC article.
Virtual screening for small-molecule pathway regulators by image-profile matching.
Rohban MH, Fuller AM, Tan C, Goldstein JT, Syangtan D, Gutnick A, DeVine A, Nijsure MP, Rigby M, Sacher JR, Corsello SM, Peppler GB, Bogaczynska M, Boghossian A, Ciotti GE, Hands AT, Mekareeya A, Doan M, Gale JP, Derynck R, Turbyville T, Boerckel JD, Singh S, Kiessling LL, Schwarz TL, Varelas X, Wagner FF, Kafri R, Eisinger-Mathason TSK, Carpenter AE. Rohban MH, et al. Among authors: ciotti ge. Cell Syst. 2022 Sep 21;13(9):724-736.e9. doi: 10.1016/j.cels.2022.08.003. Epub 2022 Sep 2. Cell Syst. 2022. PMID: 36057257 Free PMC article.
Small Extracellular Vesicles Promote Stiffness-mediated Metastasis.
Sneider A, Liu Y, Starich B, Du W, Nair PR, Marar C, Faqih N, Ciotti GE, Kim JH, Krishnan S, Ibrahim S, Igboko M, Locke A, Lewis DM, Hong H, Karl MN, Vij R, Russo GC, Gómez-de-Mariscal E, Habibi M, Muñoz-Barrutia A, Gu L, Eisinger-Mathason TSK, Wirtz D. Sneider A, et al. Among authors: ciotti ge. Cancer Res Commun. 2024 May 9;4(5):1240-1252. doi: 10.1158/2767-9764.CRC-23-0431. Cancer Res Commun. 2024. PMID: 38630893 Free PMC article.
Small extracellular vesicles promote stiffness-mediated metastasis.
Sneider A, Liu Y, Starich B, Du W, Marar C, Faqih N, Ciotti GE, Kim JH, Krishnan S, Ibrahim S, Igboko M, Locke A, Lewis DM, Hong H, Karl M, Vij R, Russo GC, Nair P, Gómez-de-Mariscal E, Habibi M, Muñoz-Barrutia A, Gu L, Eisinger-Mathason TSK, Wirtz D. Sneider A, et al. Among authors: ciotti ge. bioRxiv [Preprint]. 2024 Mar 28:2023.07.01.545937. doi: 10.1101/2023.07.01.545937. bioRxiv. 2024. Update in: Cancer Res Commun. 2024 May 9;4(5):1240-1252. doi: 10.1158/2767-9764.CRC-23-0431 PMID: 37425743 Free PMC article. Updated. Preprint.