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Regulation of human microglial gene expression and function via RNAase-H active antisense oligonucleotides in vivo in Alzheimer's disease.
Vandermeulen L, Geric I, Fumagalli L, Kreir M, Lu A, Nonneman A, Premereur J, Wolfs L, Policarpo R, Fattorelli N, De Bondt A, Van Den Wyngaert I, Asselbergh B, Fiers M, De Strooper B, d'Ydewalle C, Mancuso R. Vandermeulen L, et al. Among authors: de strooper b, de bondt a. Mol Neurodegener. 2024 Apr 24;19(1):37. doi: 10.1186/s13024-024-00725-9. Mol Neurodegener. 2024. PMID: 38654375 Free PMC article.
Microglia states and nomenclature: A field at its crossroads.
Paolicelli RC, Sierra A, Stevens B, Tremblay ME, Aguzzi A, Ajami B, Amit I, Audinat E, Bechmann I, Bennett M, Bennett F, Bessis A, Biber K, Bilbo S, Blurton-Jones M, Boddeke E, Brites D, Brône B, Brown GC, Butovsky O, Carson MJ, Castellano B, Colonna M, Cowley SA, Cunningham C, Davalos D, De Jager PL, de Strooper B, Denes A, Eggen BJL, Eyo U, Galea E, Garel S, Ginhoux F, Glass CK, Gokce O, Gomez-Nicola D, González B, Gordon S, Graeber MB, Greenhalgh AD, Gressens P, Greter M, Gutmann DH, Haass C, Heneka MT, Heppner FL, Hong S, Hume DA, Jung S, Kettenmann H, Kipnis J, Koyama R, Lemke G, Lynch M, Majewska A, Malcangio M, Malm T, Mancuso R, Masuda T, Matteoli M, McColl BW, Miron VE, Molofsky AV, Monje M, Mracsko E, Nadjar A, Neher JJ, Neniskyte U, Neumann H, Noda M, Peng B, Peri F, Perry VH, Popovich PG, Pridans C, Priller J, Prinz M, Ragozzino D, Ransohoff RM, Salter MW, Schaefer A, Schafer DP, Schwartz M, Simons M, Smith CJ, Streit WJ, Tay TL, Tsai LH, Verkhratsky A, von Bernhardi R, Wake H, Wittamer V, Wolf SA, Wu LJ, Wyss-Coray T. Paolicelli RC, et al. Among authors: de jager pl, de strooper b. Neuron. 2022 Nov 2;110(21):3458-3483. doi: 10.1016/j.neuron.2022.10.020. Neuron. 2022. PMID: 36327895 Free PMC article. Review.
microRNA-132 regulates gene expression programs involved in microglial homeostasis.
Walgrave H, Penning A, Tosoni G, Snoeck S, Davie K, Davis E, Wolfs L, Sierksma A, Mars M, Bu T, Thrupp N, Zhou L, Moechars D, Mancuso R, Fiers M, Howden AJM, De Strooper B, Salta E. Walgrave H, et al. Among authors: de strooper b. iScience. 2023 May 6;26(6):106829. doi: 10.1016/j.isci.2023.106829. eCollection 2023 Jun 16. iScience. 2023. PMID: 37250784 Free PMC article.
The γ-secretase substrate proteome and its role in cell signaling regulation.
Hou P, Zielonka M, Serneels L, Martinez-Muriana A, Fattorelli N, Wolfs L, Poovathingal S, T'Syen D, Balusu S, Theys T, Fiers M, Mancuso R, Howden AJM, De Strooper B. Hou P, et al. Among authors: de strooper b. Mol Cell. 2023 Nov 16;83(22):4106-4122.e10. doi: 10.1016/j.molcel.2023.10.029. Epub 2023 Nov 16. Mol Cell. 2023. PMID: 37977120 Free article.
Proteome-wide analysis identifies plasma immune regulators of amyloid-beta progression.
Duggan MR, Gomez GT, Joynes CM, Bilgel M, Chen J, Fattorelli N, Hohman TJ, Mancuso R, Cordon J, Castellano T, Koran MEI, Candia J, Lewis A, Moghekar A, Ashton NJ, Kac PR, Karikari TK, Blennow K, Zetterberg H, Martinez-Muriana A, De Strooper B, Thambisetty M, Ferrucci L, Gottesman RF, Coresh J, Resnick SM, Walker KA. Duggan MR, et al. Among authors: de strooper b. Brain Behav Immun. 2024 Aug;120:604-619. doi: 10.1016/j.bbi.2024.07.002. Epub 2024 Jul 6. Brain Behav Immun. 2024. PMID: 38977137 Free article.
Deep proteomic analysis of microglia reveals fundamental biological differences between model systems.
Lloyd AF, Martinez-Muriana A, Davis E, Daniels MJD, Hou P, Mancuso R, Brenes AJ, Sinclair LV, Geric I, Snellinx A, Craessaerts K, Theys T, Fiers M, De Strooper B, Howden AJM. Lloyd AF, et al. Among authors: de strooper b. Cell Rep. 2024 Oct 25;43(11):114908. doi: 10.1016/j.celrep.2024.114908. Online ahead of print. Cell Rep. 2024. PMID: 39460937 Free article.
Neurodegeneration cell per cell.
Balusu S, Praschberger R, Lauwers E, De Strooper B, Verstreken P. Balusu S, et al. Among authors: de strooper b. Neuron. 2023 Mar 15;111(6):767-786. doi: 10.1016/j.neuron.2023.01.016. Epub 2023 Feb 13. Neuron. 2023. PMID: 36787752 Free article. Review.
406 results