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JAK-STAT signaling maintains homeostasis in T cells and macrophages.
Fortelny N, Farlik M, Fife V, Gorki AD, Lassnig C, Maurer B, Meissl K, Dolezal M, Boccuni L, Ravi Sundar Jose Geetha A, Akagha MJ, Karjalainen A, Shoebridge S, Farhat A, Mann U, Jain R, Tikoo S, Zila N, Esser-Skala W, Krausgruber T, Sitnik K, Penz T, Hladik A, Suske T, Zahalka S, Senekowitsch M, Barreca D, Halbritter F, Macho-Maschler S, Weninger W, Neubauer HA, Moriggl R, Knapp S, Sexl V, Strobl B, Decker T, Müller M, Bock C. Fortelny N, et al. Among authors: meissl k. Nat Immunol. 2024 May;25(5):847-859. doi: 10.1038/s41590-024-01804-1. Epub 2024 Apr 24. Nat Immunol. 2024. PMID: 38658806 Free PMC article.
The good and the bad faces of STAT1 in solid tumours.
Meissl K, Macho-Maschler S, Müller M, Strobl B. Meissl K, et al. Cytokine. 2017 Jan;89:12-20. doi: 10.1016/j.cyto.2015.11.011. Epub 2015 Nov 26. Cytokine. 2017. PMID: 26631912 Free article. Review.
STAT1 Isoforms Differentially Regulate NK Cell Maturation and Anti-tumor Activity.
Meissl K, Simonović N, Amenitsch L, Witalisz-Siepracka A, Klein K, Lassnig C, Puga A, Vogl C, Poelzl A, Bosmann M, Dohnal A, Sexl V, Müller M, Strobl B. Meissl K, et al. Front Immunol. 2020 Sep 11;11:2189. doi: 10.3389/fimmu.2020.02189. eCollection 2020. Front Immunol. 2020. PMID: 33042133 Free PMC article.
Oncogenic TYK2 P760L kinase is effectively targeted by combinatorial TYK2, mTOR and CDK4/6 kinase blockade.
Woess K, Macho-Maschler S, Van Ingen Schenau DS, Butler M, Lassnig C, Valcanover D, Poelzl A, Meissl K, Maurer B, Brandstoetter T, Vogl C, Koren A, Kubicek S, Orlova A, Moriggl R, Strobl B, Sexl V, Van Leeuwen FN, Kuiper RP, Mueller M. Woess K, et al. Among authors: meissl k. Haematologica. 2023 Apr 1;108(4):993-1005. doi: 10.3324/haematol.2021.279848. Haematologica. 2023. PMID: 35021603 Free PMC article.
In vivo tumor surveillance by NK cells requires TYK2 but not TYK2 kinase activity.
Prchal-Murphy M, Witalisz-Siepracka A, Bednarik KT, Putz EM, Gotthardt D, Meissl K, Sexl V, Müller M, Strobl B. Prchal-Murphy M, et al. Among authors: meissl k. Oncoimmunology. 2015 May 26;4(11):e1047579. doi: 10.1080/2162402X.2015.1047579. eCollection 2015 Nov. Oncoimmunology. 2015. PMID: 26451322 Free PMC article.
T-Bet Controls Cellularity of Intestinal Group 3 Innate Lymphoid Cells.
Schroeder JH, Meissl K, Hromadová D, Lo JW, Neves JF, Howard JK, Helmby H, Powell N, Strobl B, Lord GM. Schroeder JH, et al. Among authors: meissl k. Front Immunol. 2021 Feb 2;11:623324. doi: 10.3389/fimmu.2020.623324. eCollection 2020. Front Immunol. 2021. PMID: 33603753 Free PMC article.
Sustained Post-Developmental T-Bet Expression Is Critical for the Maintenance of Type One Innate Lymphoid Cells In Vivo.
Schroeder JH, Roberts LB, Meissl K, Lo JW, Hromadová D, Hayes K, Zabinski T, Read E, Moreira Heliodoro C, Reis R, Howard JK, Grencis RK, Neves JF, Strobl B, Lord GM. Schroeder JH, et al. Among authors: meissl k. Front Immunol. 2021 Oct 29;12:760198. doi: 10.3389/fimmu.2021.760198. eCollection 2021. Front Immunol. 2021. PMID: 34795671 Free PMC article.
28 results