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A translational framework to DELIVER nanomedicines to the clinic.
Joyce P, Allen CJ, Alonso MJ, Ashford M, Bradbury MS, Germain M, Kavallaris M, Langer R, Lammers T, Peracchia MT, Popat A, Prestidge CA, Rijcken CJF, Sarmento B, Schmid RB, Schroeder A, Subramaniam S, Thorn CR, Whitehead KA, Zhao CX, Santos HA. Joyce P, et al. Among authors: whitehead ka. Nat Nanotechnol. 2024 Nov;19(11):1597-1611. doi: 10.1038/s41565-024-01754-7. Epub 2024 Sep 6. Nat Nanotechnol. 2024. PMID: 39242807 Review.
Lipid Nanoparticle-Associated Inflammation is Triggered by Sensing of Endosomal Damage: Engineering Endosomal Escape Without Side Effects.
Omo-Lamai S, Wang Y, Patel MN, Essien EO, Shen M, Majumdar A, Espy C, Wu J, Channer B, Tobin M, Murali S, Papp TE, Maheshwari R, Wang L, Chase LS, Zamora ME, Arral ML, Marcos-Contreras OA, Myerson JW, Hunter CA, Tsourkas A, Muzykantov V, Brodsky I, Shin S, Whitehead KA, Gaskill P, Discher D, Parhiz H, Brenner JS. Omo-Lamai S, et al. Among authors: whitehead ka. bioRxiv [Preprint]. 2024 Apr 18:2024.04.16.589801. doi: 10.1101/2024.04.16.589801. bioRxiv. 2024. PMID: 38659905 Free PMC article. Preprint.
Lipid nanoparticle structure and delivery route during pregnancy dictate mRNA potency, immunogenicity, and maternal and fetal outcomes.
Chaudhary N, Newby AN, Arral ML, Yerneni SS, LoPresti ST, Doerfler R, Petersen DMS, Montoya C, Kim JS, Fox B, Coon T, Malaney A, Sadovsky Y, Whitehead KA. Chaudhary N, et al. Among authors: whitehead ka. Proc Natl Acad Sci U S A. 2024 Mar 12;121(11):e2307810121. doi: 10.1073/pnas.2307810121. Epub 2024 Mar 4. Proc Natl Acad Sci U S A. 2024. PMID: 38437545 Free PMC article.
Characterization and comparison of human and mouse milk cells.
Doerfler R, Yerneni S, Newby A, Chaudhary N, Shu A, Fein K, Hofstatter Azambuja J, Whitehead KA. Doerfler R, et al. Among authors: whitehead ka. PLoS One. 2024 Jan 31;19(1):e0297821. doi: 10.1371/journal.pone.0297821. eCollection 2024. PLoS One. 2024. PMID: 38295101 Free PMC article.
124 results